67566-54-5Relevant articles and documents
Co(III)-Catalyzed Coupling-Cyclization of Aryl C-H Bonds with α-Diazoketones Involving Wolff Rearrangement
Hu, Xinwei,Chen, Xun,Shao, Youxiang,Xie, Haisheng,Deng, Yuanfu,Ke, Zhuofeng,Jiang, Huanfeng,Zeng, Wei
, p. 1308 - 1312 (2018)
An unusual cobalt(III)-catalyzed cross-coupling/cyclization of aryl C-H bonds of N-nitrosoanilines with α-diazo-β-ketoesters has been achieved. This protocol features a unique combination of Csp2-H activation/Wolff rearrangement process, allowing for the rapid assembly of quaternary 2-oxindoles. The empirical evidence and density functional theory (DFT) calculations reveal the trapping process of transient acceptor ketene intermediates by cobalt metallocycles.