67602-09-9Relevant articles and documents
Regioselective addition of Grignard reagents to N-acylpyrazinium salts: Synthesis of substituted 1,2-dihydropyrazines and Δ5-2-oxopiperazines
St Hilaire, Valentine R.,Hopkins, William E.,Miller, Yenteeo S.,Dandepally, Srinivasa R.,Williams, Alfred L.
supporting information, p. 72 - 78 (2019/01/28)
The regioselective addition of Grignard reagents to mono- and disubstituted N-acylpyrazinium salts affording substituted 1,2-dihy-dropyrazines in modest to excellent yields (45–100%) is described. Under acidic conditions, these 1,2-dihydropyrazines can be converted to substituted Δ5-2-oxopiperazines providing a simple and efficient approach towards their preparation.
Studies on Pyrazines. Part 10. Substitution Effect on Reaction of Pyrazine N-Oxides with Phosphoryl chloride
Sato, Nobuhiro
, p. 2860 - 2875 (2007/10/02)
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