67614-68-0Relevant articles and documents
Process for preparing 4,5,6,7-tetrahydro-7-oxobenzo[b]thiophenes and 1,2,3,4-tetrahydro-4-oxonaphthalenes
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, (2008/06/13)
There is provided a process for the preparation of an amido or an ureido derivative of certain 4,5,6,7-tetrahydro-7-oxobenzo[b]thiophenes or certain 1,2,3,4-tetrahydro-4-oxonaphthalenes which can be employed as an animal growth regulant. The process comprises: oxidizing in the presence of a cobalt catalyst a compound having the formula: STR1 wherein R1 and R2 are each a substituent selected from the group consisting of alkanoyl C1 -C7, halogen-substituted alkanoyl C1 -C7, carboalkoxy C1 -C4, STR2 and STR3 R3 is selected from the group consisting of hydrogen and alkyl C1 -C4 ; R4 is selected from the group consisting of hydr ogen, alkyl C1 -C8, alkanoyl C2 -C4, halogen-substituted alkanoyl (C2 -C4), and STR4 and when the STR5 moiety is cyclized each represents a moiety selected from the group consisting of succinimido, maleimido and phthalimido; X and Y are each a radical selected from the group consisting of hydrogen, fluorine, chlorine, bromine, iodine, nitro, alkyl C1 -C4 ; the racemic mixtures and the optical isomers thereof.