676256-25-0Relevant articles and documents
NOVEL ALK2 INHIBITORS AND METHODS FOR INHIBITING BMP SIGNALING
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Paragraph 00563, (2018/11/22)
The present invention provides small-molecule inhibitors of BMP signaling and compositions and methods for inhibiting BMP signaling. These compounds and compositions may be used to modulate cell growth, differentiation, proliferation, and apoptosis, and thus may be useful for treating diseases or conditions associated with BMP signaling, including inflammation, cardiovascular disease, hematological disease, cancer, and bone disorders, as well as for modulating cellular differentiation and/or proliferation. These compounds and compositions may also be used to treat subjects with Sjogren's syndrome, or diffuse intrinsic pontine glioma (DIPG).
THIAZOLONES FOR USE AS PI3 KINASE INHIBITORS
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, (2008/06/13)
Invented is a method of inhibiting the activity/function of PI3 kinases using substituted thiazolones. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, ne
NOVEL CHEMICAL COMPOUNDS
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, (2010/11/25)
This invention relates to newly identified compounds for inhibiting hYAK3 proteins and methods for treating diseases associated with hYAK3 activity.