676256-39-6

Basic information

• Product Name: tertiary butyl 7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-(3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-(E)-6-heptenoate
• Synonyms: tertiary butyl 7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-(3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-(E)-6-heptenoate
• CAS NO: 676256-39-6
• Molecular Weight: 649.9
• Mol File: 676256-39-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: tertiary butyl 7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-(3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-(E)-6-heptenoate(CAS DataBase Reference)
• NIST Chemistry Reference: tertiary butyl 7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-(3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-(E)-6-heptenoate(676256-39-6)
• EPA Substance Registry System: tertiary butyl 7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-(3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-(E)-6-heptenoate(676256-39-6)

Safety Data

• Hazardous Substances Data: 676256-39-6(Hazardous Substances Data)

Upstream product

• 128237-30-9 1-tert-butyl 5-ethyl 3-hydroxypentanedioate 
• 615556-98-4 tert-butyl (3R)-3-(tert-butyldimethylsilyloxy)-6-dimethoxyphosphinyl-5-oxohexanate 
• 147118-37-4 N-[4-(4-fluorophenyl)-5-formyl-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide 
• 105876-28-6 (R)-4-cyano-3-(tert-butyldimethylsilyloxy)butyric acid 
• 141942-82-7 (R)-(-)-ethyl 4-cyano-3-(tert-butyldimethylsilyloxy)butyrate 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 141942-85-0 (R)-ethyl 4-cyano-3-hydroxybutyrate 
• 908274-88-4 C₃₄H₄₅O₄PSi 

Downstream Products

• 355806-00-7 rosuvastatin tert-butyl ester 

Relevant articles and documents

Method for preparing of chiral intermediate and method for the preparing of HMG-CoA reductase inhibitor using chiral intermadiate

Chiral compounds and manufacturing method of the present invention refers to using the same manufacturing method relates to number of HMG-COa reduction inhibitors, more specifically an HMG-COa-reduction inhibitors number jaws statin compound in number of chiral intermediates that can be used a reaction steps, mild, and endangering a simple method and in high yield and purity can be under trillion number, purity statin compound is mirror number under trillion number on a commercial scale in can manufacturing method and [...] compounds using the same number of HMG-COa reduction inhibitors relates to manufacturing method. (by machine translation)

PREPARATION OF ROSUVASTATIN

Provided are processes for preparing intermediates of rosuvastatin and their use in preparation of rosuvastatin and rosuvastatin salts thereof.