67657-77-6

Basic information

• Product Name: 5,6-trans-1α-Acetoxyvitamin D₃
• Synonyms: 5,6-trans-1α-Acetoxyvitamin D₃
• CAS NO: 67657-77-6
• Molecular Weight: 442.682
• Mol File: 67657-77-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5,6-trans-1α-Acetoxyvitamin D₃(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-trans-1α-Acetoxyvitamin D₃(67657-77-6)
• EPA Substance Registry System: 5,6-trans-1α-Acetoxyvitamin D₃(67657-77-6)

Safety Data

• Hazardous Substances Data: 67657-77-6(Hazardous Substances Data)

Upstream product

• 67657-75-4 1α-Acetoxy-3,5-cyclovitamin D₃ 
• 57733-78-5 Vitamin D₃ tosylate 
• 67657-73-2 1α-Hydroxy-3,5-cyclovitamin D₃ 
• 67710-68-3 3,5-Cyclovitamin D₃ 
• 67-97-0 Vitamin D₃ 

Downstream Products

• 65445-14-9 5,6-trans-1α-Hydroxyvitamin D₃ 

Relevant articles and documents

Direct C(1) Hydroxylation of Vitamin D3 and Related Compounds

A direct synthesis of C(1) hydroxylated vitamin D analogues from the corresponding vitamin D precursors has been developed.Allylic oxidation of 3,5-cyclovitamin D derivatives, readily obtained from the buffered solvolysis of vitamin D tosylates, with selenium dioxide yields 1α-hydroxylated 3,5-cyclovitamin D compounds which are smoothly converted to the desired 1α-hydroxyvitamin D derivatives by acid-catalyzed cycloreversion.Application of this scheme to vitamin D3 (1a), 25-hydroxyvitamin D3 (1b), and vitamin D2 (1c) affords the 1α-hydroxy products in ca.20 percent overall yield.