67659-37-4

Basic information

• Product Name: (S)-(-)-1,1-DIPHENYL-2-AMINOPROPANE
• Synonyms: (S)-(-)-1,1-DIPHENYL-2-AMINOPROPANE;(S)-1,1-DIPHENYL-2-AMINOPROPANE;(S)-1-METHYL-2,2-DIPHENYL-ETHYLAMINE;(S)-(-)-2-AMINO-1,1-DIPHENYLPROPANE;(S)-1,1-Diphenyl-2-propanamine;(S)-1,1-Diphenylpropan-2-aMine;Benzeneethanamine, .alpha.-methyl-.beta.-phenyl-, (.alpha.S)-;(S)-(-)-1,1-Diphenyl-2-aminopropane 97%
• CAS NO: 67659-37-4
• Molecular Formula: C₁₅H₁₇N
• Molecular Weight: 211.3
• Product Categories: Amines;Chiral Building Blocks;Organic Building Blocks
• Mol File: 67659-37-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 78-82 °C(lit.)
• Boiling Point: 324.161 °C at 760 mmHg
• Flash Point: 150.039 °C
• Appearance: /
• Density: 1.022 g/cm³
• Storage Temp.: 2-8°C
• PKA: 9.21±0.10(Predicted)
• CAS DataBase Reference: (S)-(-)-1,1-DIPHENYL-2-AMINOPROPANE(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(-)-1,1-DIPHENYL-2-AMINOPROPANE(67659-37-4)
• EPA Substance Registry System: (S)-(-)-1,1-DIPHENYL-2-AMINOPROPANE(67659-37-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 67659-37-4(Hazardous Substances Data)

Usage

Description

(S)-(-)-1,1-DIPHENYL-2-AMINOPROPANE is a chiral amine compound characterized by its unique molecular structure, featuring two phenyl groups attached to a central carbon atom, which is bonded to a nitrogen atom. (S)-(-)-1,1-DIPHENYL-2-AMINOPROPANE is known for its distinct stereochemistry, with the "S" configuration indicating the arrangement of the phenyl and amino groups in three-dimensional space.

Uses

Used in Chirality Sensing Studies:
(S)-(-)-1,1-DIPHENYL-2-AMINOPROPANE is used as a model amine compound for chirality sensing studies. It serves as a valuable tool in the development and testing of organic probes that utilize circular dichroism techniques to detect and analyze chiral molecules. This application is crucial in various fields, including pharmaceuticals, where the stereochemistry of a compound can significantly impact its biological activity and efficacy.

Upstream product

• 3139-55-7 1,1-diphenylisopropylamine 
• 78603-91-5 (S)-2-amino-1,1-diphenylpropan-1-ol 
• 191090-29-6 (S)-4-Methyl-5,5-diphenyl-oxazolidin-2-one 

Downstream Products

• 1301743-12-3 C₇₈H₅₆N₂ 
• 1250258-75-3 N-((S)-1,1-diphenylpropan-2-yl)pivalamide 

Relevant articles and documents

COMPOSITIONS AND METHODS FOR CYCLOFRUCTANS AS SEPARATION AGENTS

The present invention relates to derivatized cyclofructan compounds, compositions comprising derivatized cyclofructan compounds, and methods of using compositions comprising derivatized cyclofructan compounds for chromatographic separations of chemical species, including enantiomers. Said compositions may comprise a solid support and/or polymers comprising derivatized cyclofructan compounds.

A short synthesis of (S)-α-(diphenylmethyl)alkyl amines from amino acids

A range of (S)-α-(diphenylmethyl)alkyl amines were prepared from the corresponding (S)-α-amino acid ester hydrochlorides. These amines were derived by direct hydrogenation of their precursor oxazolidinones.