677-43-0 Usage
Description
N,N-Dimethylphosphoramidodichloridate, also known as a chemical intermediate, is a compound that plays a significant role in the synthesis of various chemical products. It is characterized by its reactivity and ability to form active intermediates, which contribute to its wide range of applications across different industries.
Uses
Used in Chemical Synthesis:
N,N-Dimethylphosphoramidodichloridate is used as a key intermediate for the synthesis of phosphoramidates and (RS)-ethyl N,N-dimethylphosphoramidocyanidate (Nerve agent GA), which is employed as a chemical weapon. Its ability to form active intermediates allows it to react with alcohols in situ to produce esters and convert primary alcohols to alkyl chlorides.
Used in Organic Synthesis:
In the field of organic synthesis, N,N-Dimethylphosphoramidodichloridate serves as an important raw material and intermediate. Its reactivity and ability to form active intermediates make it a valuable component in the development of various organic compounds.
Used in Pharmaceuticals:
N,N-Dimethylphosphoramidodichloridate is used as a crucial intermediate in the pharmaceutical industry. Its involvement in the synthesis of various pharmaceutical compounds contributes to the development of new drugs and treatments.
Used in Agrochemicals:
In the agrochemical industry, N,N-Dimethylphosphoramidodichloridate plays a significant role as a raw material and intermediate. Its use in the synthesis of agrochemical products helps in the development of effective solutions for agricultural applications.
Used in Dye Industry:
N,N-Dimethylphosphoramidodichloridate is also utilized in the dye industry as a key intermediate. Its reactivity and ability to form active intermediates contribute to the production of various dyes and pigments.
Additionally, N,N-Dimethylphosphoramidodichloridate reacts with 1,2 diols to prepare cyclic phosphoric amides, which can be further reduced to produce alkenes, expanding its applications in various chemical reactions and processes.
Check Digit Verification of cas no
The CAS Registry Mumber 677-43-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,7 and 7 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 677-43:
(5*6)+(4*7)+(3*7)+(2*4)+(1*3)=90
90 % 10 = 0
So 677-43-0 is a valid CAS Registry Number.
InChI:InChI=1/C2H6Cl2NOP/c1-5(2)7(3,4)6/h1-2H3
677-43-0Relevant articles and documents
REACTION OF 1,1-DICHLORO-1-NITROSOBUTANE WITH N,N-DIMETHYLAMIDODICHLOROPHOSPHITE
Sokolov, V. B.,Ivanov, A. N.,Epishina, T. A.,Martynov, I. V.
, p. 1296 - 1298 (1989)
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A cyclic phosphorus method for preparing cooperates the effect halogen-free flame retardant,
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Paragraph 0019; 0028-0032, (2017/02/17)
The invention relates to a preparation method of a cyclic phosphorus-nitrogen synergistic halogen-free flame retardant, particularly a preparation method of 2,7-di(N,N-dimethylamino)-1,6,3,8,2,7-octahydrodioxadiazolyldiphosphinic acid, belonging to the field of preparation of novel halogen-free flame retardants. The method comprises the following steps: by using an organic solvent as a solvent and alkali as an acid-binding agent, stirring phosphorus oxychloride and dimethylamine hydrochloride to react at -25-0 DEG C until no white precipitate is generated; leaving the low-temperature environment, naturally heating the reaction system to room temperature, and continuing the reaction at room temperature for 2-5 hours; carrying out vacuum filtration to remove the precipitate, thereby obtaining a filtrate; and carrying out secondary heating, and carrying out vacuum filtration to remove the precipitate, thereby obtaining the 2,7-di(N,N-dimethylamino)-1,6,3,8,2,7-octahydrodioxadiazolyldiphosphinic acid. The method has the advantages of simple technique and low cost, can easily implement industrial production, and has wide market application prospects.
Synthesis and antitumor activity of nonsymmetric phosphoric acid triamides
Kosykhova,Palaima,Stumbryavichyute
, p. 525 - 527 (2007/10/03)
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