67736-30-5Relevant articles and documents
Conversion of ω-Guanidino- and ω-Ureido-α-amino Acids into α-Keto Acids and Heterocycles Derived Therefrom
Klein, Christian,Schulz, Guenter,Steglich, Wolfgang
, p. 1623 - 1637 (2007/10/02)
Treatment of basic α-amino acids 1 with trifluoroacetic anhydride readily leads to 2-trifluoromethyl-3-oxazolin-5-ones 2, which in turn may be hydrolyzed to yield α-keto acids 4 under mild conditions.Type 4 compounds carrying ω-guanidino or ω-ureido funct