6775-66-2

Basic information

• Product Name: 2,5-DICHLOROBENZENESULFONOHYDRAZIDE
• Synonyms: 2,5-DICHLOROBENZENESULFONOHYDRAZIDE;IVK/9068040;ZINC02531009
• CAS NO: 6775-66-2
• Molecular Formula: C₆H₆Cl₂N₂O₂S
• Molecular Weight: 241.09504
• Mol File: 6775-66-2.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,5-DICHLOROBENZENESULFONOHYDRAZIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-DICHLOROBENZENESULFONOHYDRAZIDE(6775-66-2)
• EPA Substance Registry System: 2,5-DICHLOROBENZENESULFONOHYDRAZIDE(6775-66-2)

Safety Data

• Hazardous Substances Data: 6775-66-2(Hazardous Substances Data)

Usage

General Description

2,5-Dichlorobenzenesulfonohydrazide, also known as 2,5-dichloro-4-carboxypentanoyl-aminobenzenesulfonamide, is a chemical compound with the molecular formula C6H4Cl2N2O2S. It is commonly used as an antimicrobial agent and fungicide in various industrial and agricultural applications. The compound functions by inhibiting the growth and reproduction of microorganisms and fungi, making it an effective additive in products such as paints, adhesives, and textiles. 2,5-Dichlorobenzenesulfonohydrazide is also used in the manufacture of polymer materials and as a chemical intermediate in the synthesis of other organic compounds. However, due to its potential health and environmental risks, proper handling and disposal of the chemical are necessary to prevent adverse effects.

Upstream product

• 5402-73-3 2,5-dichlorobenzenesulphonyl chloride 

Downstream Products

• 88522-50-3 C₁₃H₉Cl₂N₃O₄S 
• 88522-51-4 C₁₃H₁₀Cl₂N₂O₃S 
• 88522-47-8 C₁₃H₁₂Cl₂N₂O₄S₂ 
• 75968-23-9 glyoxylic acid 2,5-dichlorobenzenesulfonylhydrazone 
• 59425-77-3 C₁₄H₁₀Cl₂ 
• 76089-71-9 2,5-dichloro-stilbene 
• 6647-37-6 2,5?dichloro?N’?(1?phenylethylidene)benzenesulfonohydrazide 
• 88522-19-4 N,N-dimethyl-2,5-dichlorobenzenesulfonamide 
• 1554261-73-2 C₁₆H₁₆Cl₂OS 
• 1448709-50-9 C₁₄H₉Cl₂NS 

Relevant articles and documents

One-pot synthesis of sulfonylhydrazones from sulfonyl chloride, hydrazine hydrate and vinyl azide in water

A facile and eco-friendly protocol for the synthesis of sulfonylhydrazones from sulfonyl chlorides, hydrazine hydrate and vinyl azides was developed. The unique advantage of this approach is that desired products can be obtained efficiently in water, which meets the requirements of green chemistry and provides good perspectives for the sustainable production of new drug candidate. Also, this reaction proceeded in moderate to good yields with a wide tolerance of functional groups.

An approach to C-N activation: Coupling of arenesulfonyl hydrazides and arenesulfonyl chlorides with: Tert -amines via a metal-, oxidant- and halogen-free anodic oxidation

tert-Amines were harnessed to afford arenesulfonyl hydrazides and arenesulfonyl chlorides via a metal-, oxidant- and halogen-free electrochemical oxidative coupling in an undivided cell at RT. This environmentally benign approach afforded a wide spectrum of sulfonamides in satisfactory yields using cheap and renewable Pencil Graphite Electrodes (PGEs).

N-arylsulfonyl hydrazones as inhibitors of IMP-1 metallo-β-lactamase

Members of a family of N-arylsulfonyl hydrazones have been identified as novel inhibitors of IMP-1, a metallo-β-lactamase of increasing prevalence. Structure-activity relationship studies have indicated a requirement for bulky aromatic substituents on each side of the sulfonyl hydrazone backbone for these compounds to serve as efficient inhibitors of IMP-1. Molecular modeling has provided insight into the structural basis for the anti-metallo-β-lactamase activity exhibited by this class of compounds.