6776-45-0

Basic information

• Product Name: 6-(5-bromo-2-hydroxyphenyl)-2-(3-bromo-4-methoxyphenyl)-4-(4-methylphenyl)-1,2,3,6-tetrahydropyrimidin-1-ium
• CAS NO: 6776-45-0
• Molecular Formula: C₂₄H₂₃Br₂N₂O₂
• Molecular Weight: 531.2591
• Mol File: 6776-45-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 608.4°C at 760 mmHg
• Flash Point: 321.8°C
• Vapor Pressure: 2.13E-15mmHg at 25°C
• CAS DataBase Reference: 6-(5-bromo-2-hydroxyphenyl)-2-(3-bromo-4-methoxyphenyl)-4-(4-methylphenyl)-1,2,3,6-tetrahydropyrimidin-1-ium(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(5-bromo-2-hydroxyphenyl)-2-(3-bromo-4-methoxyphenyl)-4-(4-methylphenyl)-1,2,3,6-tetrahydropyrimidin-1-ium(6776-45-0)
• EPA Substance Registry System: 6-(5-bromo-2-hydroxyphenyl)-2-(3-bromo-4-methoxyphenyl)-4-(4-methylphenyl)-1,2,3,6-tetrahydropyrimidin-1-ium(6776-45-0)

Safety Data

• Hazardous Substances Data: 6776-45-0(Hazardous Substances Data)

Upstream product

• 60-35-5 acetamide 
• 433-27-2 ethyl trifluoroacetaldehyde hemiacetal 
• 431-46-9 2,2,2-trifluoro-1-methoxy-ethanol 
• 75-90-1 2,2,2-Trifluoroacetaldehyde 

Relevant articles and documents

A direct approach to α-trifluoromethylamines

(Matrix presented) S-[1-(N-Acetylamino)-2,2,2-trifluoroethyl]-O-ethyl dithiocarbonate (6), a readily available xanthate, adds efficiently to various functionalized olefins to give the corresponding adducts 8 via a radical chain reaction initiated by a small amount of lauroyl peroxide.

A xanthate-transfer approach to - Trifluoromethylamines [2-(N-acetylamino)-4,4-dimethoxy-1,1,1-trifluorobutane]

-

N-Acyl-1-chloro-2,2,2-trifluoroethylamine as a 2,2,2-Trifluoroethylamine-Building Block

The reactions of N-benzoyl- and N-acetyl-1-chloro-2,2,2-trifluoroethylamines with various carbonnucleophiles gave the corresponding 1-substituted N-acyl-2,2,2-trifluoroethylamines in good yields and the efficient reactivity was applied on the synthesis of