6778-50-3

Basic information

• Product Name: 1,2,3,4-tetra-O-trimethysilyl-α-L-rhamnose
• CAS NO: 6778-50-3
• Molecular Weight: 452.886
• Mol File: 6778-50-3.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: 1,2,3,4-tetra-O-trimethysilyl-α-L-rhamnose(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3,4-tetra-O-trimethysilyl-α-L-rhamnose(6778-50-3)
• EPA Substance Registry System: 1,2,3,4-tetra-O-trimethysilyl-α-L-rhamnose(6778-50-3)

Safety Data

• Hazardous Substances Data: 6778-50-3(Hazardous Substances Data)

Upstream product

• 88434-24-6 marthasteroside A₂ 
• 75-77-4 chloro-trimethyl-silane 
• 2280-44-6 D-Glucose 
• 73-34-7 D-Fucose 
• 3615-41-6 L-Rhamnose 
• 18156-74-6 1-(Trimethylsilyl)imidazole 
• 1307292-22-3 (25R)-26-O-β-D-glucopyranosyl-furosta-5,20(22)-diene-1β,3β,26-triol 1-O-[α-L-rhamnopyranosyl-(1->2)-O-α-L-arabinopyranoside] 
• 73-34-7 L-rhamnose 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 1268813-04-2 mirabamide F 
• 1268813-03-1 mirabamide E 
• 1300063-95-9 2α,3β,23,30-tetrahydroxyurs-12-en-28-oic acid 28-O-[α-L-rhamnopyranosyl-(1->4)-β-D-glucopyranosyl-(1->6)-β-D-glucopyranosyl] ester 

Relevant articles and documents

New steroidal saponins from the roots of Solanum melongena L.

Phytochemical investigation of the roots of Solanum melongena L. resulted in the isolation of six new steroidal saponins, including five new cholestane saponins (1-5) and one new steroidal alkaloid (6), along with one new natural product (7) and three know steroids (8-10). The structures of all isolated compounds were determined by 1D and 2D NMR experiments and by comparison of their spectroscopic and physical data with literature values. The inhibitory activities on nitric oxide (NO) production stimulated by lipopolysaccharide (LPS) in a RAW 264.7 cell line were assayed for all the isolated compounds. Compounds 1, 2 and 4–9 exhibited moderate inhibition of NO production with IC50 values ranging from 12.6 to 59.5 μM.

An efficient method for the preparation of 1,5-anhydroalditol from unprotected carbohydrates via glycopyranosyl iodide

A practical, facile method was developed for the preparation of 1,5-anhydroalditol via per-O-TMS-glycopyranosyl iodide with LiBH4. A series of 1,5-anhydroalditols were prepared in excellent yields (up to 92%) from unprotected carbohydrates within 2 days under mild conditions. In addition, multi-gram scale preparation of 1,5-anhydroglucitol (1,5-AG), a major polyol present in human serum, was developed using the same procedure without the need for chromatographic purification.

Furostanol saponins from the seeds of Allium cepa L.

Allium cepa L. is one of the most widely cultivated and used plants. In addition to its bulb (onion), which is used as food in many cultures, the seeds of A. cepa L. are used as a traditional herbal medicine by the Uygur nationality in China to treat diarrhea and promote blood flow. In a bioactivity-screening, the ethanol extract of seeds of A. cepa L. showed inhibitory effects on protein tyrosine phosphatase 1B (PTP1B) enzyme, with 81.1% inhibition. Phytochemical investigation of the ethanol extract of red onion (Allium cepa L.) seeds led to the isolation of eight new furostanol saponins, named ceparosides E-L (1-8). Their structures were established using 1D and 2D NMR spectroscopy, mass spectrometry and chemical methods. Compounds 1-8 were screened for inhibitory effects on the PTP1B enzyme and cytotoxic activity against five human cells, including HCT-8, Bel-7402, BGC-823, A549 and A2780, but all were found to be inactive.