67800-62-8

Basic information

• Product Name: Oxiranemethanol, methanesulfonate, (S)-
• CAS NO: 67800-62-8
• Molecular Formula: C4H8O4S
• Molecular Weight: 152.171
• Mol File: 67800-62-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Oxiranemethanol, methanesulfonate, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxiranemethanol, methanesulfonate, (S)-(67800-62-8)
• EPA Substance Registry System: Oxiranemethanol, methanesulfonate, (S)-(67800-62-8)

Safety Data

• Hazardous Substances Data: 67800-62-8(Hazardous Substances Data)

Downstream Products

• 85564-76-7 (αS, 2R) 1-(2-exo-bicyclo<2,2,1>hept-2-ylphenoxy)-3-<(1-methylethyl)amino>-2-propanol 
• 85564-66-5 (αS, 2S) 1-(2-exo-bicyclo<2,2,1>hept-2-ylphenoxy)-3-<(1-methylethyl)amino>-2-propanol 
• 51997-51-4 4-(2,3-epoxypropoxy)carbazole 

Relevant articles and documents

Process for the preparation of optically-active carbazole derivatives, new R- and S-carbazole derivatives and pharmaceutical compositions containing these compounds

A process for the preparation of S- or R-carbazole derivatives of the general formula: STR1 in which R is an unsubstituted or substituted amino radical and pharmacologically acceptable salts, by either reacting R-(-)-epichlorohydrin (for the S-carbazole derivative); or reacting an S-epoxide derivative of the general formula: STR2 in which R1 is the residue of a substituted sulphonic acid derivative (for the R-carbazole derivative); with 4-hydroxycarbazole and then with ammonia or a substituted amine of the general formula RH, and recovering the compound or converting it to a pharmacologically acceptable salt. The new R-(+)- and S(-)-carbazole derivatives provided by the inventive process have unexpected beta blocking and vasodilatory properties and are useful in pharmaceutical compositions. R-(+)-carbazole derivatives are also useful for the treatment of glaucoma.