67808-66-6

Basic information

• Product Name: Methyl 2-formyl-4-thiophenecarboxylate
• Synonyms: METHYL 5-FORMYLTHIOPHENE-3-CARBOXYLATE;METHYL 2-FORMYLTHIOPHENE-4-CARBOXYLATE;METHYL 2-FORMYL-4-THIOPHENECARBOXYLATE;3-THIOPHENECARBOXYLIC ACID, 5-FORMYL-, METHYL ESTER;2-FORMYLTHIOPHENE-4-CARBOXYLIC ACID METHYL ESTER;5-Formyl-3-Thiophene Carboxylic Acid Methylester;5-Formylthiophene-3-carboxylic acid methyl ester;2-FORMYLTHIOPHENE-4-CARBOXYLIC
• CAS NO: 67808-66-6
• Molecular Formula: C₇H₆O₃S
• Molecular Weight: 170.19
• EINECS: 625-266-0
• Product Categories: Aromatic Esters;Aldehydes;Thiophenes & Benzothiophenes;Esters;Thiophene&Benzothiophene;Miscellaneous;Thiophenes & Benzothiophenes
• Mol File: 67808-66-6.mol
• Article Data: 5

Chemical Properties

• Melting Point: 113-116°C
• Boiling Point: 296 °C at 760 mmHg
• Flash Point: 132.8 °C
• Appearance: /
• Density: 1.327 g/cm³
• Vapor Pressure: 0.0016mmHg at 25°C
• Refractive Index: 1.581
• Sensitive: Air Sensitive
• CAS DataBase Reference: Methyl 2-formyl-4-thiophenecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 2-formyl-4-thiophenecarboxylate(67808-66-6)
• EPA Substance Registry System: Methyl 2-formyl-4-thiophenecarboxylate(67808-66-6)

Safety Data

• Hazardous Substances Data: 67808-66-6(Hazardous Substances Data)

Usage

General Description

Methyl 2-formyl-4-thiophenecarboxylate is a chemical compound with the molecular formula C7H6O3S. It belongs to the class of organic compounds known as thiophene carboxylic acids and derivatives. This specific compound has a thiophene ring, a five-membered aromatic ring with one sulfur atom. In the molecular structure, the carboxylic acid derivative is an ester (methyl ester) and there's also an aldehyde group attached to the ring. Due to the combination of these functional groups, this compound might be involved in various organic synthesis applications. However, detailed information on its uses, toxicity, and safety is not widely documented, implying that it is more likely used in specialized chemical research or industry.

InChI:InChI=1/C7H6O3S/c1-5(9)10-6-2-7(3-8)11-4-6/h2-4H,1H3

Upstream product

• 58267-85-9 2-(4-bromo-thiophen-2-yl)-[1,3]dioxolane 
• 89324-44-7 3-carboxy-thiophene-5-carboxaldehyde 
• 74-88-4 methyl iodide 

Downstream Products

• 191934-27-7 methyl 5-(bromomethyl)thiophene-3-carboxylate 
• 882004-79-7 5-[(5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]non-9-ylmethyl]thiophen-3-carboxylic acid methyl ester hydrochloride salt 

Relevant articles and documents

TRICYCLIC PIPERIDINE COMPOUNDS

The present invention relates to compounds of the formula (I) wherein R1a, R1b, R2, R3, (R4)n and ring (A) are as described in the description, to their preparation, to pharmaceutically acc

TRICYCLIC PIPERIDINE COMPOUNDS

The present invention relates to compounds of the formula (I), wherein R, R1a, R1b, R2, R3, and X are as described in the description, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), to methods for the preparation of such compounds of formula (I), and especially to their use as TPH modulators.

3-SUBSTITUTED-2-OXINDOLE DERIVATIVES

This invention relates to novel 3-substituted-2-oxindole derivatives which are inhibitors of prostaglandin H 2 synthase, 5-lipoxygenase and interleukin-1 biosynthesis. The compounds of the invention are useful as inhibitors of prostaglandin H 2 synthase and interleukin-1 biosynthesis, per se, and as analgesic, antiinflammatory and antiarthritic agents in the treatment of chronic inflammatory diseases. This invention also relates to pharmaceutical compositions comprising said 3-substituted-2-oxindole derivatives; to methods of inhibiting prostaglandin H 2 synthase and biosynthesis of interleukin-1; and to treating chronic inflammatory diseases in a mammal with said compounds. Further, this invention relates to certain novel carboxylic acids useful as intermediates in the preparation of the 3-substituted-2-oxindole derivatives of this invention and to a process for the preparation of the 3-substituted-2-oxindole derivatives.