6784-61-8Relevant articles and documents
Theoretical and model studies on the chemoselectivity of a Grignard reagent's reaction with a combined aminonitrile-oxazolidine system
Aitken, David J,Beaufort, Virginie,Chalard, Pierre,Cladière, Jean-Luc,Dufour, Monique,Pereira, Elisabeth,Théry, Vincent
, p. 5933 - 5940 (2002)
Semi-empirical quantum chemical studies using PM3 suggest that the preferred reaction between a Grignard reagent and a combined aminonitrile-oxazolidine system involves initial formation of a Lewis acid-base complex between magnesium and the central nitrogen atom, followed by preferred reaction with the aminonitrile function; model studies confirm that this reaction proceeds by addition rather than substitution.
Glycerol as a Building Block for Prochiral Aminoketone, N-Formamide, and N-Methyl Amine Synthesis
Dai, Xingchao,Rabeah, Jabor,Yuan, Hangkong,Brückner, Angelika,Cui, Xinjiang,Shi, Feng
, p. 3133 - 3138 (2016/11/29)
Prochiral aminoketones are key intermediates for the synthesis of optically active amino alcohols, and glycerol is one of the main biomass-based alcohols available in industry. In this work, glycerol was catalytically activated and purposefully converted with amines to generate highly valuable prochiral aminoketones, as well as N-formamides and N-methyl amines, over CuNiAlOx catalyst. The catalyst structure can be anticipated as nano-Ni species on or in CuAlOx via the formation of nano- Cu?Ni alloy particles. This concept may present a novel and valuable methodology for glycerol utilization.
Highly chemoselective α-diazo carbonyl insertion reactions into N-H and S-H bonds catalysed by [RuCl(η5-C5H5)(PPh3)2]
Del Zotto, Alessandro,Baratta, Walter,Rigo, Pierluigi
, p. 3079 - 3082 (2007/10/03)
Complex [RuCl(η5-C5H5)(PPh3)2], in chloroform at 60 deg C, catalyses the chemoselective insertion of α-diazo carbonyl compounds into N-H and S-H bonds to afford α-keto-amines and α-keto-thioethers.
