67865-68-3

Basic information

• Product Name: Z-L-Ala-CHN2
• Synonyms: Z-L-ALA-CHN2
• CAS NO: 67865-68-3
• Molecular Formula: C₁₂H₁₃N₃O₃
• Molecular Weight: 247.24992
• Mol File: 67865-68-3.mol
• Article Data: 22

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Z-L-Ala-CHN2(CAS DataBase Reference)
• NIST Chemistry Reference: Z-L-Ala-CHN2(67865-68-3)
• EPA Substance Registry System: Z-L-Ala-CHN2(67865-68-3)

Safety Data

• Hazardous Substances Data: 67865-68-3(Hazardous Substances Data)

Usage

General Description

Z-L-Ala-CHN2 is a chemical compound that is a derivative of Z-Ala, a modified form of the amino acid alanine. The compound contains a carbonyl group and a nitrogen-containing group, making it a potent inhibitor of proteolytic enzymes. It is commonly used in research settings to study the efficacy of enzyme inhibitors and their potential therapeutic applications. Additionally, Z-L-Ala-CHN2 has been shown to possess anti-inflammatory properties and could potentially be used as a targeted treatment for conditions involving excessive protease activity. Overall, the compound shows promise as a valuable tool for studying enzyme function and as a potential therapeutic agent.

Upstream product

• 186581-53-3 diazomethane 
• 1142-20-7 N-Cbz-Ala 
• 49760-60-3 N-benzyloxycarbonyl-L-alanyl chloride 
• 501-53-1 benzyl chloroformate 
• 65638-93-9 N-Carbobenzoxy-L-alanin-kohlensaeureaethylesteranhydrid 
• 25172-67-2 Z-Ala-O-COO-isoBu 

Downstream Products

• 83460-84-8 methyl (3S)-3-{[(benzyloxy)carbonyl]amino}butanoate 
• 1402729-94-5 Z-L-Ala-CH₂CN 
• 1427161-74-7 C₂₄H₂₆N₄O₂S 
• 1616868-61-1 (S)-3-benzyloxycarbonylaminobutane-1-sulfonic acid 
• 1616868-40-6 (S)-3-(benzyloxycarbonylamino)butyl methanesulfonate 
• 1616868-53-1 (S)-S-3-(benzyloxycarbonylamino)butyl ethanethioate 
• 128913-38-2 ((1S,2S)-2-Hydroxy-1-methyl-3-phenylsulfanyl-propyl)-carbamic acid benzyl ester 
• 159141-65-8 (2S,3S)-1-chloro-3-(benzyloxycarbonylamino)-2-butanol 
• 159141-73-8 threo N-Cbz-alanyl epoxide 
• 83509-91-5 (S)-3-[(S)-3-((S)-3-Benzyloxycarbonylamino-butyrylamino)-butyrylamino]-butyric acid methyl ester 
• 83509-90-4 (S)-3-Benzyloxycarbonylamino-butyric acid 2,4,5-trichloro-phenyl ester 
• 83460-92-8 (S)-3-((S)-3-Benzyloxycarbonylamino-butyrylamino)-butyric acid methyl ester 
• 83460-93-9 (S)-3-((S)-3-Benzyloxycarbonylamino-butyrylamino)-butyric acid 
• 83460-94-0 (S)-3-((S)-3-Benzyloxycarbonylamino-butyrylamino)-butyric acid 2,4,5-trichloro-phenyl ester 

Relevant articles and documents

α-Xanthylmethyl Ketones from α-Diazo ketones

A simple and efficient method to obtain α-xanthylmethyl ketones from α-diazo ketones is described. The reaction proceeds through a protonation/nucleophilic substitution sequence in the presence of p -toluenesulfonic acid and potassium ethyl xanthogenate as the nucleophile. As α-diazo ketones can be readily synthesized from ubiquitous carboxylic acids, a broad variety of xanthates can be obtained, including examples from naturally occurring substrates.

Continuous flow synthesis of β-amino acids from α-amino acids via Arndt-Eistert homologation

A fully continuous four step process for the preparation of β-amino acids from their corresponding α-amino acids utilizing the Arndt-Eistert homologation approach is described. the Partner Organisations 2014.

1,5-rhodium shift in rearrangement of N -arenesulfonylazetidin-3-ols into benzosultams

Benzosultams are synthesized in an enantiopure form starting from α-amino acids through a rhodium-catalyzed rearrangement reaction of N-arenesulfonylazetidin-3-ols. Mechanistically, this reaction involves C-C bond cleavage by β-carbon elimination and C-H bond cleavage by a 1,5-rhodium shift.