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67952-60-7

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67952-60-7 Usage

Chemical Properties

clear light yellow liquid

Check Digit Verification of cas no

The CAS Registry Mumber 67952-60-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,9,5 and 2 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 67952-60:
(7*6)+(6*7)+(5*9)+(4*5)+(3*2)+(2*6)+(1*0)=167
167 % 10 = 7
So 67952-60-7 is a valid CAS Registry Number.
InChI:InChI=1/C5H10OS2/c1-5(2,4-6)8-7-3/h4H,1-3H3

67952-60-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-methyl-2-(methyldisulfanyl)propanal

1.2 Other means of identification

Product number -
Other names EINECS 267-914-1

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Food additives -> Flavoring Agents
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:67952-60-7 SDS

67952-60-7Synthetic route

2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

glycine ethyl ester hydrochloride
623-33-6

glycine ethyl ester hydrochloride

(2-methyl-2-methyldisulfanyl-propylideneamino)-acetic acid ethyl ester
1350644-69-7

(2-methyl-2-methyldisulfanyl-propylideneamino)-acetic acid ethyl ester

Conditions
ConditionsYield
With magnesium sulfate; triethylamine In dichloromethane at 20℃;95%
2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

bis(3-isopropylpyrazol-1-yl)methanone

bis(3-isopropylpyrazol-1-yl)methanone

C17H28N4S2
936476-37-8

C17H28N4S2

Conditions
ConditionsYield
With cobalt(II) chloride at 130℃; for 18h;79%
2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

methylamine
74-89-5

methylamine

C6H15NS2
1239587-72-4

C6H15NS2

Conditions
ConditionsYield
Stage #1: 2-methyl-2-(methyldithio)propionaldehyde; methylamine In ethanol at 20℃; for 4h;
Stage #2: With sodium tetrahydroborate; ethanol at 0℃;		65%
2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

(3-amino-5-hydroxymethylphenyl)methanol
71176-54-0

(3-amino-5-hydroxymethylphenyl)methanol

(5-(2-methyl-2-(methyldisulfanyl)propylamino)-1,3-phenylene)dimethanol

(5-(2-methyl-2-(methyldisulfanyl)propylamino)-1,3-phenylene)dimethanol

Conditions
ConditionsYield
Stage #1: 2-methyl-2-(methyldithio)propionaldehyde; (3-amino-5-hydroxymethylphenyl)methanol In ethanol at 20℃; for 3h;
Stage #2: With sodium tetrahydroborate In ethanol at 0℃; for 1h;		65%
2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

bis-(3,5-dimethylpyrazolyl)methanone
50476-17-0

bis-(3,5-dimethylpyrazolyl)methanone

C15H24N4S2

C15H24N4S2

Conditions
ConditionsYield
With cobalt(II) chloride at 80℃; for 3h; Condensation;56%
2,2'-carbonylbis(4,5,6,7-tetrahydro-7,8,8-trimethyl-4,7-methano-indazole)

2,2'-carbonylbis(4,5,6,7-tetrahydro-7,8,8-trimethyl-4,7-methano-indazole)

2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

2-[bis(4,5,6,7-tetrahydro-7,8,8-trimethyl-4,7-methano-2-indazolyl)methyl](1-methyl-1-sulfanylethyl)methane
1115475-30-3

2-[bis(4,5,6,7-tetrahydro-7,8,8-trimethyl-4,7-methano-2-indazolyl)methyl](1-methyl-1-sulfanylethyl)methane

Conditions
ConditionsYield
With pyridine at 80℃; for 15h; Peterson reaction;48%
2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

(S)-9-hydroxy-8-methoxy-11,12,12a,13-tetrahydro-6H-benzo[5,6][1,4]diazepino[1,2-a]indol-6-one

(S)-9-hydroxy-8-methoxy-11,12,12a,13-tetrahydro-6H-benzo[5,6][1,4]diazepino[1,2-a]indol-6-one

C22H26N2O3S2

C22H26N2O3S2

Conditions
ConditionsYield
With sodium tris(acetoxy)borohydride In 1,2-dichloro-ethane at 20℃; for 48h;43%
2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

3,5-bis(((tert-butyldimethylsilyl)oxy)methyl)-N-(2-(2-(2-methoxyethoxyl)ethoxy)ethyl)aniline
1239588-01-2

3,5-bis(((tert-butyldimethylsilyl)oxy)methyl)-N-(2-(2-(2-methoxyethoxyl)ethoxy)ethyl)aniline

3,5-bis(((tert-butyldimethylsilyl)oxy)methyl)-N-(2-(2-(2-methoxyethoxyl)ethoxy)ethyl)-N-(2-methyl-2-(methyldisulfanyl)propyl)aniline

3,5-bis(((tert-butyldimethylsilyl)oxy)methyl)-N-(2-(2-(2-methoxyethoxyl)ethoxy)ethyl)-N-(2-methyl-2-(methyldisulfanyl)propyl)aniline

Conditions
ConditionsYield
With sodium tris(acetoxy)borohydride; magnesium sulfate; zinc(II) chloride In 1,2-dichloro-ethane at 20℃; for 25h;40%
2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

(5-(2-(2-(2-methoxyethoxy)ethoxy)ethylamino)-1,3-phenylene)dimethanol
1239587-69-9

(5-(2-(2-(2-methoxyethoxy)ethoxy)ethylamino)-1,3-phenylene)dimethanol

(5-((2-(2-(2-methoxyethoxyl)ethoxy)ethyl)(2-methyl-2-(methyldisulfanyl)propyl)amino)-1,3-phenylene)dimethanol

(5-((2-(2-(2-methoxyethoxyl)ethoxy)ethyl)(2-methyl-2-(methyldisulfanyl)propyl)amino)-1,3-phenylene)dimethanol

Conditions
ConditionsYield
With sodium tris(acetoxy)borohydride; magnesium sulfate; zinc(II) chloride In 1,2-dichloro-ethane at 20℃; for 23h;22%
With sodium tris(acetoxy)borohydride; magnesium sulfate; zinc(II) chloride at 20℃;22%
1,1'-sulfinylbis(camphorpyrazole)

1,1'-sulfinylbis(camphorpyrazole)

2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

2-[bis(4,5,6,7-tetrahydro-7,8,8-trimethyl-4,7-methano-2-indazolyl)methyl](1-methyl-1-sulfanylethyl)methane
1115475-30-3

2-[bis(4,5,6,7-tetrahydro-7,8,8-trimethyl-4,7-methano-2-indazolyl)methyl](1-methyl-1-sulfanylethyl)methane

Conditions
ConditionsYield
With pyridine In tetrahydrofuran for 16h; Reflux;4.49 g
2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

[3-methoxy-2-(1-methyl-1-methyldisulfanyl-ethyl)-4-oxoazetidin-1-yl]-acetic acid ethyl ester
1350644-70-0

[3-methoxy-2-(1-methyl-1-methyldisulfanyl-ethyl)-4-oxoazetidin-1-yl]-acetic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: magnesium sulfate; triethylamine / dichloromethane / 20 °C
2: triethylamine / dichloromethane / 2 h / Reflux
View Scheme
2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

4-{2-[{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethyl}-(2-methyl-2-methyldisulfanyl-propyl)-amino]-ethoxy}-2,6-bis-(hydroxy methyl)-pyridine
1356864-56-6

4-{2-[{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethyl}-(2-methyl-2-methyldisulfanyl-propyl)-amino]-ethoxy}-2,6-bis-(hydroxy methyl)-pyridine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: titanium(IV) isopropylate / tetrahydrofuran / 2.33 h / 20 °C
1.2: 1.75 h / 20 °C
2.1: potassium carbonate / N,N-dimethyl-formamide / 36 h / 60 - 80 °C
View Scheme
2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

C23H42N2O10S4

C23H42N2O10S4

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: titanium(IV) isopropylate / tetrahydrofuran / 2.33 h / 20 °C
1.2: 1.75 h / 20 °C
2.1: potassium carbonate / N,N-dimethyl-formamide / 36 h / 60 - 80 °C
3.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 0.33 h / -20 °C
View Scheme
2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

4-{2-[{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethyl}-(2-methyl-2-methyldisulfanyl-propyl)-amino]-ethoxy}-2,6-bis-[(S)-2-eth-(E)-ylidene-7-methoxy-1,2,3,11a-tetrahydropyrrolo[2,1c][1,4]benzodiazepin-5-one-8-yloxymethyl]-pyridine
1356864-55-5

4-{2-[{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethyl}-(2-methyl-2-methyldisulfanyl-propyl)-amino]-ethoxy}-2,6-bis-[(S)-2-eth-(E)-ylidene-7-methoxy-1,2,3,11a-tetrahydropyrrolo[2,1c][1,4]benzodiazepin-5-one-8-yloxymethyl]-pyridine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: titanium(IV) isopropylate / tetrahydrofuran / 2.33 h / 20 °C
1.2: 1.75 h / 20 °C
2.1: potassium carbonate / N,N-dimethyl-formamide / 36 h / 60 - 80 °C
3.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 0.33 h / -20 °C
4.1: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 12 h / 30 °C
View Scheme
2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

4-[2-amino-ethoxy]-2,6-bis-(hydroxymethyl)-pyridine
1234259-89-2

4-[2-amino-ethoxy]-2,6-bis-(hydroxymethyl)-pyridine

4-[2-(2-methyl-2-methyldisulfanyl-propylamino)-ethoxy]-2,6-bis-(hydroxymethyl)-pyridine
1268593-61-8

4-[2-(2-methyl-2-methyldisulfanyl-propylamino)-ethoxy]-2,6-bis-(hydroxymethyl)-pyridine

Conditions
ConditionsYield
Stage #1: 2-methyl-2-(methyldithio)propionaldehyde; 4-[2-amino-ethoxy]-2,6-bis-(hydroxymethyl)-pyridine With titanium(IV) isopropylate In tetrahydrofuran at 20℃; for 2.33333h;
Stage #2: With ethanol; sodium cyanoborohydride In tetrahydrofuran at 20℃; for 1.75h;
Stage #1: 2-methyl-2-(methyldithio)propionaldehyde; 4-[2-amino-ethoxy]-2,6-bis-(hydroxymethyl)-pyridine With titanium(IV) isopropylate In tetrahydrofuran at 20℃; for 2.33333h;
Stage #2: With ethanol; sodium cyanoborohydride In tetrahydrofuran for 1.75h;
O-methylhydroxylamine chloride
123219-29-4

O-methylhydroxylamine chloride

2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

2-Methyl-2-methyldisulfanylpropionaldehyde O-methyloxime

2-Methyl-2-methyldisulfanylpropionaldehyde O-methyloxime

Conditions
ConditionsYield
With NaOH In ethanol; water
2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

1-t-Butoxycarbonylpiperazine
57260-71-6

1-t-Butoxycarbonylpiperazine

tert-Butyl 4-(2-methyl-2-methyldisulfanylpropyl)piperazine-1-carboxylate
1260139-55-6

tert-Butyl 4-(2-methyl-2-methyldisulfanylpropyl)piperazine-1-carboxylate

Conditions
ConditionsYield
With sodium cyanoborohydride; titanium(IV) isopropylate In tetrahydrofuran; ethanol; water; ethyl acetate
2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

Methyl[2-methyl-2-methyldisulfanylprop-(E)-ylidene]amine
1260430-82-7

Methyl[2-methyl-2-methyldisulfanylprop-(E)-ylidene]amine

Conditions
ConditionsYield
With methylamine In tetrahydrofuran; ethyl acetate
2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

tert-Butyl methyl[2-(2-{2-[2-(2-methyl-2-methyldisulfanylpropylamino)ethoxy]-ethoxy}ethoxy)ethyl]carbamate
1260430-87-2

tert-Butyl methyl[2-(2-{2-[2-(2-methyl-2-methyldisulfanylpropylamino)ethoxy]-ethoxy}ethoxy)ethyl]carbamate

Conditions
ConditionsYield
With sodium hydroxide; sodium tris(acetoxy)borohydride; acetic acid In 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran; isopropyl alcohol
2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

4-{2-[methyl(2-methyl-2-(methyldisulphanyl)propyl)amino]ethoxy}-2,6-bis(hydroxymethyl)pyridine
1268593-59-4

4-{2-[methyl(2-methyl-2-(methyldisulphanyl)propyl)amino]ethoxy}-2,6-bis(hydroxymethyl)pyridine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: titanium(IV) isopropylate / tetrahydrofuran / 2.33 h / 20 °C
1.2: 1.75 h
2.1: formic acid / 1.25 h / 0 - 100 °C
2.2: 20 °C / pH 12
View Scheme
2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

4-{2-[methyl(2-methyl-2-methyldisulphanylpropyl)amino]ethoxy}-2,6-bis[(S)-2-eth-(E)-ylidene-7-methoxy-1,2,3,11a-tetrahydropyrrolo[2,1-c][1,4]benzodiazepin-5-one-8-yloxymethyl]pyridine

4-{2-[methyl(2-methyl-2-methyldisulphanylpropyl)amino]ethoxy}-2,6-bis[(S)-2-eth-(E)-ylidene-7-methoxy-1,2,3,11a-tetrahydropyrrolo[2,1-c][1,4]benzodiazepin-5-one-8-yloxymethyl]pyridine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: titanium(IV) isopropylate / tetrahydrofuran / 2.33 h / 20 °C
1.2: 1.75 h
2.1: formic acid / 1.25 h / 0 - 100 °C
2.2: 20 °C / pH 12
3.1: triethylamine; methanesulfonyl chloride / dichloromethane / 0.5 h / -25 °C
3.2: 2 h / 30 °C
View Scheme
titanium(IV) isopropylate
546-68-9

titanium(IV) isopropylate

2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

4-[2-amino-ethoxy]-2,6-bis-(hydroxymethyl)-pyridine
1234259-89-2

4-[2-amino-ethoxy]-2,6-bis-(hydroxymethyl)-pyridine

4-[2-(2-methyl-2-methyldisulfanyl-propylamino)-ethoxy]-2,6-bis-(hydroxymethyl)-pyridine
1268593-61-8

4-[2-(2-methyl-2-methyldisulfanyl-propylamino)-ethoxy]-2,6-bis-(hydroxymethyl)-pyridine

Conditions
ConditionsYield
With sodium hydroxide; sodium cyanoborohydride In tetrahydrofuran; hydrogenchloride; ethanol liquid HCl;
2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

C54H59N5O9S2

C54H59N5O9S2

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium tris(acetoxy)borohydride; zinc(II) chloride; magnesium sulfate / 1,2-dichloro-ethane / 23 h / 20 °C
2: triethylamine / dichloromethane / 1 h / -10 - -7 °C
3: potassium carbonate / N,N-dimethyl-formamide / 20 °C
View Scheme
Multi-step reaction with 3 steps
1: sodium tris(acetoxy)borohydride; zinc(II) chloride; magnesium sulfate / 20 °C
2: methanesulfonyl chloride; triethylamine / dichloromethane / 1.25 h / -10 - -7 °C
3: potassium carbonate / N,N-dimethyl-formamide / 20 °C
View Scheme
2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

(5-((2-(2-(2-methoxyethoxyl)ethoxy)ethyl)(2-methyl-2-(methyldisulfanyl)propyl)amino)-1,3-phenylene)bis(methylene)dimethanesulfonate

(5-((2-(2-(2-methoxyethoxyl)ethoxy)ethyl)(2-methyl-2-(methyldisulfanyl)propyl)amino)-1,3-phenylene)bis(methylene)dimethanesulfonate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium tris(acetoxy)borohydride; zinc(II) chloride; magnesium sulfate / 1,2-dichloro-ethane / 23 h / 20 °C
2: triethylamine / dichloromethane / 1 h / -10 - -7 °C
View Scheme
Multi-step reaction with 2 steps
1: sodium tris(acetoxy)borohydride; zinc(II) chloride; magnesium sulfate / 20 °C
2: methanesulfonyl chloride; triethylamine / dichloromethane / 1.25 h / -10 - -7 °C
View Scheme
2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

(S)-8-methoxy-9-((3-((((S)-8-methoxy-6-oxo-11,12,12a,13-tetrahydro-6H-benzo[5,6][1,4]diazepino[1,2-a]indol-9-yl)oxy)methyl)-5-((2-(2-(2-methoxyethoxy)ethoxy)ethyl)(2-methyl-2-(methyldisulfanyl)propyl)amino)benzyl)oxy)-12a,13-dihydro-6H-benzo[5,6][1,4]diazepino[1,2-a]indol-6-one

(S)-8-methoxy-9-((3-((((S)-8-methoxy-6-oxo-11,12,12a,13-tetrahydro-6H-benzo[5,6][1,4]diazepino[1,2-a]indol-9-yl)oxy)methyl)-5-((2-(2-(2-methoxyethoxy)ethoxy)ethyl)(2-methyl-2-(methyldisulfanyl)propyl)amino)benzyl)oxy)-12a,13-dihydro-6H-benzo[5,6][1,4]diazepino[1,2-a]indol-6-one

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: sodium tris(acetoxy)borohydride; zinc(II) chloride; magnesium sulfate / 1,2-dichloro-ethane / 23 h / 20 °C
2: triethylamine / dichloromethane / 1 h / -10 - -7 °C
3: potassium carbonate / N,N-dimethyl-formamide / 20 °C
4: 5-ethyl-2-methylpyridine borane complex / dichloromethane; ethanol / 1 h / 20 °C
View Scheme
Multi-step reaction with 5 steps
1: sodium tris(acetoxy)borohydride; zinc(II) chloride; magnesium sulfate / 1,2-dichloro-ethane / 23 h / 20 °C
2: triethylamine / dichloromethane / 1 h / -10 - -7 °C
3: sodium iodide / acetone / 2 h
4: potassium carbonate / acetone / 20 °C / Sealed tube
5: potassium carbonate / acetone / 20 °C / Sealed tube
View Scheme
2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

A

(S)-8-methoxy-9-((3-((((S)-8-methoxy-6-oxo-11,12,12a,13-tetrahydro-6H-benzo[5,6][1,4]diazepino[1,2-a]indol-9-yl)oxy)methyl)-5-((2-(2-(2-methoxyethoxy)ethoxy)ethyl)(2-methyl-2-(methyldisulfanyl)propyl)amino)benzyl)oxy)-12a,13-dihydro-6H-benzo[5,6][1,4]diazepino[1,2-a]indol-6-one

(S)-8-methoxy-9-((3-((((S)-8-methoxy-6-oxo-11,12,12a,13-tetrahydro-6H-benzo[5,6][1,4]diazepino[1,2-a]indol-9-yl)oxy)methyl)-5-((2-(2-(2-methoxyethoxy)ethoxy)ethyl)(2-methyl-2-(methyldisulfanyl)propyl)amino)benzyl)oxy)-12a,13-dihydro-6H-benzo[5,6][1,4]diazepino[1,2-a]indol-6-one

B

C54H63N5O9S2

C54H63N5O9S2

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: sodium tris(acetoxy)borohydride; zinc(II) chloride; magnesium sulfate / 1,2-dichloro-ethane / 23 h / 20 °C
2: triethylamine / dichloromethane / 1 h / -10 - -7 °C
3: potassium carbonate / N,N-dimethyl-formamide / 20 °C
4: sodium tetrahydroborate / dichloromethane; ethanol / 3 h / 0 - 20 °C
View Scheme
Multi-step reaction with 4 steps
1: sodium tris(acetoxy)borohydride; zinc(II) chloride; magnesium sulfate / 20 °C
2: methanesulfonyl chloride; triethylamine / dichloromethane / 1.25 h / -10 - -7 °C
3: potassium carbonate / N,N-dimethyl-formamide / 20 °C
4: sodium tetrahydroborate; ethanol / dichloromethane / 3.08 h / 0 - 20 °C
View Scheme
2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

C54H63N5O9S2

C54H63N5O9S2

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: sodium tris(acetoxy)borohydride; zinc(II) chloride; magnesium sulfate / 1,2-dichloro-ethane / 23 h / 20 °C
2: triethylamine / dichloromethane / 1 h / -10 - -7 °C
3: potassium carbonate / N,N-dimethyl-formamide / 20 °C
4: sodium tris(acetoxy)borohydride / dichloromethane / 1.5 h / 20 °C
View Scheme
2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

3,5-bis(iodomethyl)-N-(2-(2-(2-methoxyethoxyl)ethoxy)ethyl)-N-(2-methyl-2-(methyldisulfanyl)propyl)aniline

3,5-bis(iodomethyl)-N-(2-(2-(2-methoxyethoxyl)ethoxy)ethyl)-N-(2-methyl-2-(methyldisulfanyl)propyl)aniline

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium tris(acetoxy)borohydride; zinc(II) chloride; magnesium sulfate / 1,2-dichloro-ethane / 23 h / 20 °C
2: triethylamine / dichloromethane / 1 h / -10 - -7 °C
3: sodium iodide / acetone / 2 h
View Scheme
2-methyl-2-(methyldithio)propionaldehyde
67952-60-7

2-methyl-2-(methyldithio)propionaldehyde

C37H46IN3O6S2

C37H46IN3O6S2

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: sodium tris(acetoxy)borohydride; zinc(II) chloride; magnesium sulfate / 1,2-dichloro-ethane / 23 h / 20 °C
2: triethylamine / dichloromethane / 1 h / -10 - -7 °C
3: sodium iodide / acetone / 2 h
4: potassium carbonate / acetone / 20 °C / Sealed tube
View Scheme

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