679809-58-6

Basic information

• Product Name: ENOXAPARIN SODIUM, EP STANDARD
• Synonyms: ENOXAPARIN SODIUM, EP STANDARD;Lovenox;Lovenox (preservative free);Unii-8nz41mik1o;Clexane;Enoxil;Klexane;Enoxaparin SodiuM EP
• CAS NO: 679809-58-6
• Molecular Formula: Unspecified
• Molecular Weight: 0
• EINECS: 232-681-7
• Product Categories: Other APIs
• Mol File: 679809-58-6.mol
• Article Data: 0

Chemical Properties

• Appearance: crystalline (fine)
• Density: 2.13g/cm3
• Storage Temp.: Room Temperature, Under inert atmosphere
• Solubility: Water (Slightly)
• CAS DataBase Reference: ENOXAPARIN SODIUM, EP STANDARD(CAS DataBase Reference)
• NIST Chemistry Reference: ENOXAPARIN SODIUM, EP STANDARD(679809-58-6)
• EPA Substance Registry System: ENOXAPARIN SODIUM, EP STANDARD(679809-58-6)

Safety Data

• Hazardous Substances Data: 679809-58-6(Hazardous Substances Data)

Usage

Description

ENOXAPARIN SODIUM, EP STANDARD is a low-molecular-mass heparin obtained by alkaline depolymerisation of the benzyl ester derivative of heparin from porcine intestinal mucosa. It is an antithrombotic agent with a higher ratio of antithrombotic activity to anticoagulant activity compared to unfractionated heparin. Enoxaparin sodium undergoes characteristic structural modifications due to the depolymerization reaction, making it a structurally complex molecule.
Used in Pharmaceutical Industry:
ENOXAPARIN SODIUM, EP STANDARD is used as an antithrombotic agent for the treatment of deep vein thrombosis, prophylaxis of ischemic complications of unstable angina and non-Q-wave myocardial infarction, and treatment of acute deep vein thrombosis.
Used in Diagnostic Industry:
ENOXAPARIN SODIUM, EP STANDARD is used as a biomarker for the diagnosis of atrial fibrillation as a cause of stroke.
Brand Name:
Lovenox (Sanofi Aventis).

Indications

Enoxaparin sodium is a gold standard for antithrombosis which has the largest number of indications among all LMWHs. Prophylaxis of vein thrombosis diseases (prevent intra-vein thrombosis), treatment of deep venous thrombosis, Prevention of thrombus formation in the in vitro circulation during hemodialysis, treatment of acute unstable angina and non-Q-wave myocardial infarction, administered with Aspirin.

Veterinary Drugs and Treatments

Enoxaparin may be useful for prophylaxis or treatment of deep vein thrombosis or pulmonary embolus. Recent pharmacokinetic work in dogs and cats, raises questions whether the drug can be effectively and practically administered long-term. In humans, it is also indicated for prevention of ischemic complications associated with unstable angina/non Q-wave MI.

InChI:InChI=1/C57H86N4O53S3.4Na/c1-11(64)58-21-25(69)36(17(7-62)100-50(21)96-5)104-54-32(76)29(73)41(44(111-54)48(83)84)109-52-23(60-13(3)66)27(71)38(19(102-52)9-97-115(87,88)89)106-56-34(78)31(75)40(43(113-56)47(81)82)108-51-22(59-12(2)65)26(70)37(18(8-63)101-51)105-55-33(77)30(74)42(45(112-55)49(85)86)110-53-24(61-14(4)67)28(72)39(20(103-53)10-98-116(90,91)92)107-57-35(114-117(93,94)95)15(68)6-16(99-57)46(79)80;;;;/h6,15,17-45,50-57,62-63,68-78H,7-10H2,1-5H3,(H,58,64)(H,59,65)(H,60,66)(H,61,67)(H,79,80)(H,81,82)(H,83,84)(H,85,86)(H,87,88,89)(H,90,91,92)(H,93,94,95);;;;/q;4*+1/p-4/t15-,17+,18+,19+,20+,21+,22+,23+,24+,25+,26+,27+,28+,29+,30+,31+,32+,33+,34+,35?,36?,37?,38?,39?,40-,41-,42-,43?,44?,45?,50-,51+,52+,53+,54+,55+,56+,57-;;;;/m0..../s1