67983-34-0Relevant articles and documents
17-PHOSPHOROUS STEROID DERIVATIVES USEFUL AS PROGESTERONE RECEPTOR MODULATORS
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Page/Page column 36, (2010/11/28)
The present invention is directed to novel 17-phosphorous steroid derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by a progesterone or glucocorticoid receptor.
Novel phosphorus-containing 17β-side chain mifepristone analogues as progesterone receptor antagonists
Jiang, Weiqin,Allan, George,Chen, Xin,Fiordeliso, James J.,Linton, Olivia,Tannenbaum, Pamela,Xu, Jun,Zhu, Peifang,Gunnet, Joseph,Demarest, Keith,Lundeen, Scott,Sui, Zhihua
, p. 949 - 954 (2007/10/03)
A novel series of steroidal compounds were designed and synthesized with various phosphorus-containing groups on the 17β-side chain as progesterone receptor antagonists. The structure-activity relationships of these compounds are discussed. Selected compo