6801-26-9

Basic information

• Product Name: 4,5α-Epoxy-17-methylmorphinan-3,14-diol
• Synonyms: 4,5α-Epoxy-17-methylmorphinan-3,14-diol
• CAS NO: 6801-26-9
• Molecular Formula: C17H21NO3
• Molecular Weight: 287.35354
• Mol File: 6801-26-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4,5α-Epoxy-17-methylmorphinan-3,14-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5α-Epoxy-17-methylmorphinan-3,14-diol(6801-26-9)
• EPA Substance Registry System: 4,5α-Epoxy-17-methylmorphinan-3,14-diol(6801-26-9)

Safety Data

• Hazardous Substances Data: 6801-26-9(Hazardous Substances Data)

Upstream product

• 76-41-5 oxymorphone 
• 54934-75-7 6β-oxymorphol 
• 180989-07-5 C₁₉H₂₃NO₅ 
• 180989-08-6 C₂₀H₂₂F₃NO₇S 

Relevant articles and documents

Synthesis, Pharmacology, and Molecular Docking Studies on 6-Desoxo-N-methylmorphinans as Potent μ-Opioid Receptor Agonists

Position 6 of the morphinan skeleton plays a key role in the μ-opioid receptor (MOR) activity in vitro and in vivo. We describe the consequence of the 6-carbonyl group deletion in N-methylmorphinan-6-ones 1-4 on ligand-MOR interaction, signaling, and antinociception. While 6-desoxo compounds 1a, 2a, and 4a show similar profiles to their 6-keto counterparts, the 6-desoxo-14-benzyloxy substituted 3a displays significantly increased MOR binding and agonist potency and a distinct binding mode compared with its analogue 3.