68014-57-3

Basic information

• Product Name: N-(2-Methylphenyl)-2,6-dimethylaniline
• Synonyms: 1',2,3'-Trimethyl[1,2'-iminobisbenzene];2,6-Dimethyl-N-(2-methylphenyl)benzenamine;N-(2-Methylphenyl)-2,6-dimethylaniline;2,6-dimethyl-N-o-tolylaniline
• CAS NO: 68014-57-3
• Molecular Formula: C₁₅H₁₇N
• Molecular Weight: 211.3
• Mol File: 68014-57-3.mol
• Article Data: 36

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-(2-Methylphenyl)-2,6-dimethylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-Methylphenyl)-2,6-dimethylaniline(68014-57-3)
• EPA Substance Registry System: N-(2-Methylphenyl)-2,6-dimethylaniline(68014-57-3)

Safety Data

• Hazardous Substances Data: 68014-57-3(Hazardous Substances Data)

Usage

General Description

N-(2-Methylphenyl)-2,6-dimethylaniline is a chemical compound with the molecular formula C15H17N. It is an organic compound classified as an aniline derivative, which is commonly used as a raw material in the production of dyes and pigments. This chemical is a pale yellow crystalline solid with a faint odor, and it is insoluble in water but soluble in organic solvents. N-(2-Methylphenyl)-2,6-dimethylaniline is a potentially hazardous substance, and exposure to it can cause skin and eye irritation, as well as harmful effects on the central nervous system. Therefore, proper safety precautions should be taken when handling this chemical.

Upstream product

• 615-37-2 ortho-methylphenyl iodide 
• 87-62-7 2,6-dimethylaniline 
• 95-49-8 2-methylchlorobenzene 
• 88-05-1 2,4,6-trimethylaniline 
• 95-46-5 2-methylphenyl bromide 
• 6781-98-2 2,6-dimethyl-1-chlorobenzene 
• 95-53-4 o-toluidine 

Relevant articles and documents

N-Heterocyclic Carbene Palladium(II) Amine Complexes: The Role of Primary Aryl- or Alkylamine Binding and Applications in the Buchwald-Hartwig Amination Reaction

N-heterocyclic carbene-palladium(II) amine complexes bearing primary aryl- or alkylamines were synthesized. The prepared complexes were characterized by single crystal X-ray diffraction as well as NMR spectroscopy. These complexes exhibited good catalytic activities for the Buchwald-Hartwig amination reaction of aryl chlorides to afford arylated anilines under mild conditions. All reactions were carried out in air and all starting materials were used as supplied without purification. 21 expected coupling products were obtained in moderate to high yields under optimum conditions.

N-Heterocyclic carbene-palladacyclic complexes: synthesis, characterization and their applications in the C-N coupling and α-arylation of ketones using aryl chlorides

N-Heterocyclic carbene-palladacyclic complexes 3 were successfully achieved in a one-pot procedure under mild conditions. The structure of 3a was unambiguously confirmed by X-ray single crystal diffraction and it was an active catalyst in the Buchwald-Hartwig amination and α-arylation of ketones even at very low catalyst loadings (0.01 mol%).

N-heterocyclic carbene-palladium complex, and preparation method and application thereof

The invention discloses an N-heterocyclic carbene-palladium complex, and a preparation method and application thereof. The N-heterocyclic carbene-palladium complex disclosed by the invention is shown in Formula (I), wherein L1 is a quinoline ligand or isoquinoline ligand, and N in the L1 is connected with Pd; L2 is an N-heterocyclic carbene ligand, and carbene carbon in the L2 is connected with the Pd; and X1 and X2 are respectively independently an anionic ligand. The N-heterocyclic carbene-palladium complex disclosed by the invention can efficiently catalyze carbon-carbon or carbon-heteroatom coupling reaction using aryl halide as a substrate. The formula is shown in the specification.