68034-75-3

Basic information

• Product Name: 3-(3-IODOPHENYL)PROPIONIC ACID
• Synonyms: 3-(3-IODOPHENYL)PROPIONIC ACID;3-(3-iodophenyl)propanoic acid;3-Iodobenzenepropanoic acid
• CAS NO: 68034-75-3
• Molecular Formula: C₉H₉IO₂
• Molecular Weight: 276.07
• Mol File: 68034-75-3.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 357℃
• Flash Point: 170℃
• Appearance: /
• Density: 1.775
• Vapor Pressure: 1.03E-05mmHg at 25°C
• Refractive Index: 1.624
• Storage Temp.: 2-8°C(protect from light)
• PKA: 4.59±0.10(Predicted)
• CAS DataBase Reference: 3-(3-IODOPHENYL)PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-IODOPHENYL)PROPIONIC ACID(68034-75-3)
• EPA Substance Registry System: 3-(3-IODOPHENYL)PROPIONIC ACID(68034-75-3)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 68034-75-3(Hazardous Substances Data)

Usage

General Description

3-(3-Iodophenyl)propionic acid is a chemical compound with the molecular formula C9H9IO2. It is a derivative of propionic acid with a 3-iodophenyl group attached to the carbon chain. 3-(3-IODOPHENYL)PROPIONIC ACID is commonly used in pharmaceutical and research applications as a precursor for the synthesis of various pharmaceutical products and intermediates. It is important as a starting material in the synthesis of drugs for the treatment of various medical conditions. In addition, it has potential applications as a building block for organic synthesis and in the development of new chemical compounds.

InChI:InChI=1/C9H9IO2/c10-8-3-1-2-7(6-8)4-5-9(11)12/h1-3,6H,4-5H2,(H,11,12)

Upstream product

• 1664-54-6 3-(3-aminophenyl)propionic acid 
• 7681-11-0 potassium iodide 
• 1664-56-8 m-aminocinnamic acid 
• 121269-65-6 ethyl 3-(3-iodophenyl)propanoate 
• 41070-12-6 3-iodocinnamic acid 
• 10039-64-2 ethyl 3-(3-aminophenyl)propanoate 
• 5396-71-4 ethyl 3-(3-nitrophenyl)acrylate 
• 555-68-0 m-Nitrocinnamic Acid 
• 57455-06-8 3-iodobenzylalcohol 
• 2033-24-1 cycl-isopropylidene malonate 
• 696-41-3 m-iodobenzaldehyde 

Relevant articles and documents

Structure-Guided Identification of DNMT3B Inhibitors

Methyltransferase 3 beta (DNMT3B) inhibitors that interfere with cancer growth are emerging possibilities for treatment of melanoma. Herein we identify small molecule inhibitors of DNMT3B starting from a homology model based on a DNMT3A crystal structure.

PYRROLE DERIVATIVE

A novel pyrrole derivative represented by the following formula (1) and a salt thereof: wherein R1 means substituted alkenyl, etc.; R2 means substituted benzoyl, etc.; and R3 to R5 each means hydrogen, alkyl, halogeno, etc. The derivative and salt have antidiabetic activity.

Protein-tyrosine phosphatase inhibitors and uses thereof

The present invention is directed to compounds of formula (I), or a pharmaceutically suitable salt or prodrug thereof, which are useful for the selective inhibition of protein tyrosine phosphatase-1B (PTP1B), and are useful for the treatment of disorders caused by overexpressed or altered protein tyrosine phosphatase 1B.