68036-36-2Relevant articles and documents
A practical method for N-alkylation of phosphinic (thio)amides with alcohols via transfer hydrogenation
Jankins, Tanner C.,Qin, Zi-Yang,Engle, Keary M.
, p. 3272 - 3281 (2019)
This manuscript describes a modular method for preparing N-alkyl phosphinic amides from primary or secondary alcohols and primary phosphinic amide (R1R2P = ONH2) nucleophiles via transfer hydrogenation. The transformation typically proceeds in excellent yields, employs conveniently available reagents, and produces water as the only byproduct.