68052-43-7Relevant articles and documents
Corresponding amine nitrile and method of manufacturing thereof
-
Paragraph 0125; 0126; 0129; 0130, (2018/05/24)
The present invention relates to a nitrile manufacturing method, which has characteristics of significantly-reduced ammonia source consumption, low environmental pressure, low energy consumption, low production cost, high nitrile purity, high nitrile yield and the like compared with the method in the prior art, wherein nitrile having a complicated structure can be obtained through the method. The present invention further relates to a method for producing a corresponding amine from the nitrile.
Corresponding amine nitrile and method of manufacturing thereof (by machine translation)
-
Paragraph 0123-0124; 0127-0128, (2017/10/22)
The invention relates to a method of manufacturing one kind of nitrile, compared with the prior art, has significantly reduced the amount of ammonia, the environmental pressure of the small, low energy consumption, low production cost, nitrile product purity and yield and the like, and can obtain more complex structure of the nitriles. The invention also relates to the corresponding amine by the nitrile manufacture method. (by machine translation)
Pyrazole NNRTIs 4: Selection of UK-453,061 (lersivirine) as a Development Candidate
Mowbray, Charles E.,Burt, Catherine,Corbau, Romuald,Gayton, Simon,Hawes, Michael,Perros, Manos,Tran, Isabelle,Price, David A.,Quinton, Faye J.,Selby, Matthew D.,Stupple, Paul A.,Webster, Rob,Wood, Anthony
scheme or table, p. 5857 - 5860 (2010/09/03)
We prepared three discreet cohorts of potent non-nucleoside HIV reverse transcriptase inhibitors (NNRTIs) based on the recently reported 3-cyanophenoxypyrazole lead 3. Several of these compounds displayed very promising anti-HIV activity in vitro, safety,