68058-22-0

Basic information

• Product Name: deoxythymidylyl-(3'->5')-deoxythymidine-(Pⁱⁿ->N)-phenylalanine ethyl ester
• CAS NO: 68058-22-0
• Molecular Weight: 721.658
• Mol File: 68058-22-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: deoxythymidylyl-(3'->5')-deoxythymidine-(Pⁱⁿ->N)-phenylalanine ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: deoxythymidylyl-(3'->5')-deoxythymidine-(Pⁱⁿ->N)-phenylalanine ethyl ester(68058-22-0)
• EPA Substance Registry System: deoxythymidylyl-(3'->5')-deoxythymidine-(Pⁱⁿ->N)-phenylalanine ethyl ester(68058-22-0)

Safety Data

• Hazardous Substances Data: 68058-22-0(Hazardous Substances Data)

Upstream product

• 1795-96-6 phenylalanine ethyl ester 
• 85590-83-6 tri-n-octylammonium salt of d(TpT) 

Relevant articles and documents

OLIGONUCLEOTIDES AND NUCLEOTIDOPEPTIDES. XLII. EFFICACY OF THE INTRAMOLECULAR INFLUENCE OF THE CARBOXY GROUPS OF AMINO ACIDS IN NUCLEOTIDYL-(P-->N)-AMINO ACIDS (PEPTIDES) AS A FUNCTION OF THEIR POSITIONS

It has been established that remote carboxy groups in nucleotidyl-(5'-->N)-β-alanine and -alanylalanine do not affect the mechanism of the cleavage of the phosphoramide center.The situation is different in the case of nucleotidyl-(5'-->Nε)-lysine.It has been shown that in the 3'-phenylalanine derivative of dTMP, the influence of the α-carboxy group of the amino acid is only half as great as in the 5'-analog.The α-carboxy groups of the amino acids in oligonucleotidyl-(Pin-->N)-amino acids also weaken the mechanism of the cleavage of the phosphoramide centers.