680596-79-6

Basic information

• Product Name: 1,4-DIOXA-SPIRO[4,5]DEC-7-EN-8-BORONIC ACID, PINACOL ESTER
• Synonyms: 1,4-DIOXA-SPIRO[4,5]DEC-7-EN-8-BORONIC ACID, PINACOL ESTER;4,4,5,5-Tetramethyl-2-(1,4-dioxaspiro[4.5]dec-7-en-8-yl)-1,3,2-dioxaborolane;1,4-Dioxaspiro[4.5]dec-7-ene, 8-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-;2-(1,4-Dioxaspiro[4.5]dec-7-en-8-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;3-hydroxy-2,3-diMethylbutan-2-yl hydrogen 1,4-dioxaspiro[4.5]dec-7-en-8-ylboronate;2-(1,4-Dioxaspiro[4.5]dec-7-en-8-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, 8-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,4-dioxaspiro[4.5]dec-7-ene;2-(1,4-Dioxaspiro[4.5]dec-8-en-8-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;1,4-Dioxaspiro[4,5]dec-7-en-8-boronic acid pinacol ester 0901
• CAS NO: 680596-79-6
• Molecular Formula: C₁₄H₂₃BO₄
• Molecular Weight: 266.14
• EINECS: 1312995-182-4
• Product Categories: blocks;BoronicAcids;Organic boronic acid
• Mol File: 680596-79-6.mol
• Article Data: 25

Chemical Properties

• Melting Point: 60-62°C
• Boiling Point: 313.9°C at 760 mmHg
• Flash Point: 143.7°C
• Appearance: /
• Density: 1.08g/cm³
• Vapor Pressure: 0.000888mmHg at 25°C
• Refractive Index: 1.491
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1,4-DIOXA-SPIRO[4,5]DEC-7-EN-8-BORONIC ACID, PINACOL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-DIOXA-SPIRO[4,5]DEC-7-EN-8-BORONIC ACID, PINACOL ESTER(680596-79-6)
• EPA Substance Registry System: 1,4-DIOXA-SPIRO[4,5]DEC-7-EN-8-BORONIC ACID, PINACOL ESTER(680596-79-6)

Safety Data

• Hazard Codes: Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• Hazardous Substances Data: 680596-79-6(Hazardous Substances Data)

Usage

General Description

1,4-DIOXA-SPIRO[4,5]DEC-7-EN-8-BORONIC ACID, PINACOL ESTER is a chemical compound that features a boronic acid functional group and a pinacol ester moiety. It is a spirocyclic compound with a boron atom at the 8th position and a six-membered cyclic ether ring. 1,4-DIOXA-SPIRO[4,5]DEC-7-EN-8-BORONIC ACID, PINACOL ESTER is characterized by its unique structure and has potential applications in organic synthesis, medicinal chemistry, and material science. It may be used as a reagent in organic transformations and as a building block for the synthesis of complex organic molecules. Additionally, its boronic acid functionality may enable it to participate in Suzuki-Miyaura cross-coupling reactions and other important synthetic transformations.

InChI:InChI=1/C14H23BO4/c1-12(2)13(3,4)19-15(18-12)11-5-7-14(8-6-11)16-9-10-17-14/h5H,6-10H2,1-4H3

Upstream product

• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 
• 170011-47-9 1,4-dioxaspiro[4.5]dec-7-en-8-yl trifluoromethanesulfonate 
• 73183-34-3 bis(pinacol)diborane 
• 4746-97-8 cyclohexanedione monoethylene ketal 

Downstream Products

• 959939-45-8 benzyl ((4-(1,4-dioxaspiro)[4.5] dec-7-en-8-yl)phenyl)carbamate 
• 760972-56-3 C₁₉H₂₃NO₃ 
• 1019928-47-2 4-((S)-4-tert-butoxycarbonyl-2-{[6-(1,4-dioxa-spiro[4.5]dec-7-en-8-yl)-2-phenyl-pyridine-4-carbonyl]-amino}-butyryl)-piperazine-1-carboxylic acid ethyl ester 
• 1089280-36-3 8-[3-(methyloxy)-4-nitrophenyl]-1,4-dioxaspiro[4.5]dec-7-ene 
• 1202389-28-3 8-(2,5-dimethyl-4-nitrophenyl)-1,4-dixoaspiro[4.5]dec-7-ene 
• 1202389-31-8 2-fluoro-5-methyl-4-(1,4-dioxaspiro[4.5]dec-7-en-8-yl)aniline 
• 1252615-88-5 [4-(1,4-dioxa-spiro[4.5]dec-7-en-8-yl)-phenyl]-acetonitrile 
• 724707-89-5 4-phenylcyclohex-3-en-1-one ethylene glycol ketal 
• 67019-46-9 8-(4-(trifluoromethoxy)phenyl)-1,4-dioxaspiro[4.5]dec-7-ene 
• 5309-15-9 8-(4-methoxyphenyl)-1,4-dioxaspiro[4.5]decane 

Relevant articles and documents

BICYCLOHEPTANE PYRROLIDINE OREXIN RECEPTOR AGONISTS

The present invention is directed to bicyclo[4.1.0]heptane pyrrolidine compounds which are agonists of orexin receptors. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which orexin receptors are involved.

Arylamine compound, pharmaceutical composition containing arylamine compound as well as preparation method and application of arylamine compound

The present invention relates to an arylamine compound of a formula (I), a pharmaceutical composition comprising the same, a preparation method of the arylamine compound and application of the pharmaceutical composition in the prevention or treatment of diseases or conditions associated with RET activity.

INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS AND USE OF SAME IN MEDICINE

The present invention relates to a compound represented by formula I, a pharmaceutical composition containing the compound of formula I, a method for inhibiting indoleamine 2,3-dioxygenase, and its use in medicine.