681249-57-0

Basic information

• Product Name: 2-(TRIFLUOROMETHYL)-5,6,7,8-TETRAHYDRO-[1,2,4]TRIAZOLO[1,5-A]PYRAZINE
• Synonyms: 2-(TRIFLUOROMETHYL)-5,6,7,8-TETRAHYDRO-[1,2,4]TRIAZOLO[1,5-A]PYRAZINE
• CAS NO: 681249-57-0
• Molecular Formula: C₆H₇F₃N₄
• Molecular Weight: 192.14
• Mol File: 681249-57-0.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Density: 1.72
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 2-(TRIFLUOROMETHYL)-5,6,7,8-TETRAHYDRO-[1,2,4]TRIAZOLO[1,5-A]PYRAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(TRIFLUOROMETHYL)-5,6,7,8-TETRAHYDRO-[1,2,4]TRIAZOLO[1,5-A]PYRAZINE(681249-57-0)
• EPA Substance Registry System: 2-(TRIFLUOROMETHYL)-5,6,7,8-TETRAHYDRO-[1,2,4]TRIAZOLO[1,5-A]PYRAZINE(681249-57-0)

Safety Data

• Hazardous Substances Data: 681249-57-0(Hazardous Substances Data)

Usage

General Description

2-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyrazine is a chemical compound containing a trifluoromethyl group and a tetrahydrotriazolopyrazine ring system. It is a heterocyclic molecule that has potential pharmaceutical applications due to its unique structure and functional groups. However, there is limited information available about its specific properties and uses. Further research and testing would be needed to fully understand the potential uses and implications of this chemical compound.

Upstream product

• 681249-55-8 2,2,2-trifluoro-N’-hydroxy-N-pyrazin-2-ylacetimidamide 
• 129476-64-8 2,2,2-trifluoro-N-(pyrazin-2-yl)acetamide 
• 681249-56-9 2-(trifluoromethyl)-5,6,7,8-tetrahydrogen-[1,2,4]triazolo[1,5-α]pyrazine 

Downstream Products

• 681249-58-1 C₂₁H₂₃F₆N₅O₃ 
• 681249-59-2 tert-butyl 2-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[1,5-a]pyrazine-7(8H)-carboxylate 

Relevant articles and documents

METHOD FOR PREPARING PARP INHIBITOR AND INTERMEDIATE THEREOF

Disclosed in the present invention is a method for preparing a poly ADP ribose polymerase (PARP) inhibitor and an intermediate thereof. The method has a high yield, has good product purity and is more favorable for industrial production.

AMINOTETRAHYDROPYRANS AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES

The present invention is directed to novel substituted aminotetrahydropyrans of structural formula I which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.

AMINOCYCLOHEXANES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES

The present invention is directed to novel substituted aminocyclohexanes which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DPP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.