68175-07-5

Basic information

• Product Name: 2-METHYL-1H-IMIDAZO[4,5-B]PYRIDINE
• Synonyms: 2-METHYL-1H-IMIDAZO[4,5-B]PYRIDINE;2-methyl-3H-imidazo[4,5-b]pyridine(SALTDATA: HCl 0.05NaCl);2-Methylimidazo[4,5-b]pyridine;2-Methylpyrido[2,3-d]imidazole;2-(1-cyclopropylethyl)-3H-iMidazo[4,5-b]pyridine
• CAS NO: 68175-07-5
• Molecular Formula: C₇H₇N₃
• Molecular Weight: 133.15
• EINECS: 200-258-5
• Mol File: 68175-07-5.mol
• Article Data: 15

Chemical Properties

• Melting Point: 189-190℃
• Boiling Point: 256℃
• Flash Point: 109℃
• Appearance: /
• Density: 1.31
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-METHYL-1H-IMIDAZO[4,5-B]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYL-1H-IMIDAZO[4,5-B]PYRIDINE(68175-07-5)
• EPA Substance Registry System: 2-METHYL-1H-IMIDAZO[4,5-B]PYRIDINE(68175-07-5)

Safety Data

• Statements: 36
• Safety Statements: 26
• HazardClass: IRRITANT
• Hazardous Substances Data: 68175-07-5(Hazardous Substances Data)

Usage

General Description

2-Methyl-1H-imidazo[4,5-b]pyridine is a chemical compound that is classified as a heterocyclic aromatic organic compound. It contains a unique fused ring structure consisting of an imidazole and pyridine ring, with a methyl group attached to the second carbon of the imidazole ring. 2-METHYL-1H-IMIDAZO[4,5-B]PYRIDINE is commonly used in research and pharmaceutical development, particularly in the synthesis of potential drug candidates. It has been studied for its potential biological and pharmacological properties, including its role as a potential anti-cancer and anti-inflammatory agent. Furthermore, it is also utilized in the development of novel materials and as a building block in organic synthesis. Overall, 2-Methyl-1H-imidazo[4,5-b]pyridine is a versatile and important chemical compound with various potential applications in the fields of medicine and materials science.

Upstream product

• 563-80-4 3-methyl-butan-2-one 
• 452-58-4 2,3-Diaminopyridine 
• 75-97-8 3,3-dimethyl-butan-2-one 
• 67-64-1 acetone 
• 103-79-7 1-phenyl-acetone 
• 141-97-9 ethyl acetoacetate 
• 64-19-7 acetic acid 
• 78-39-7 Triethyl orthoacetate 
• 124-42-5 acetamidine hydrochloride 
• 113975-22-7 2-fluoro-3-iodopyridine 
• 623-51-8 ethyl 2-sulfanylacetate 
• 99314-99-5 2-acetylamino-3-aminopyridine 
• 4214-75-9 2-amino-3-nitropyridine 
• 87888-52-6 <(amino-2)pyridinyl-3> amino-4 pentene-3 one-2 

Downstream Products

• 1086423-62-2 7-chloro-2-methyl-3H-imidazo[4,5-b]pyridine 
• 1312715-94-8 (E)-2-(4-cyanostyryl)-1H-imidazo[4,5-b]pyridine 

Relevant articles and documents

Access to 2-pyridinylamide and imidazopyridine from 2-fluoropyridine and amidine hydrochloride

Under catalyst-free conditions, an efficient method to synthesize 2-pyridinylamides has been developed, and the protocol uses inexpensive and readily available 2-fluoropyridine and amidine derivatives as the starting materials. Simultaneously, the copper-catalysed approach to imidazopyridine derivatives has been established with high chemoselectivity and regiospecificity. The results suggest that the nitrogen-heterocycles containing iodide substituents can also be compatible for the reaction via the cascade Ullmann-type coupling, and the nucleophilic substitution reaction provides the target products in a one-pot manner.

Gadolinium (III) chloride catalyzed facile synthesis of 2-substituted benzimidazoles under solvent-free conditions

A series of 2-substituted benzimidazoles have been prepared from o-diamines and 1,3-dicarbonyl compounds using Gadolinium chloride as a catalyst under solvent free condition in good yields. Gadolinium chloride has been demonstrated as a mild and efficient catalyst.

Novel strategy for synthesis of substituted benzimidazo[1,2-a]quinolines

An efficient method for the synthesis of benzimidazo[1,2-a]quinolines under transition-metal-free conditions has been developed through a cascade reaction involving sequential aromatic nucleophilic substitution and intramolecular Knoevenagel condensation reactions. This method is applicable for the synthesis of a wide range of benzimidazo[1,2-a]quinoline derivatives from readily available 2-fluoroarylaldehyde and benzimidazole substrates.