68223-64-3

Basic information

• Product Name: 4-FLUOROCYCLOHEXANONE
• Synonyms: 4-FLUOROCYCLOHEXANONE;4-fluorocyclohexan-1-one;Cyclohexanone, 4-fluoro-
• CAS NO: 68223-64-3
• Molecular Formula: C₆H₉FO
• Molecular Weight: 116.14
• Mol File: 68223-64-3.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 164.4±33.0℃ (760 Torr)
• Flash Point: 54.2±15.6℃
• Appearance: /
• Density: 1.03±0.1 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 1.972mmHg at 25°C
• Refractive Index: 1.414
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-FLUOROCYCLOHEXANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-FLUOROCYCLOHEXANONE(68223-64-3)
• EPA Substance Registry System: 4-FLUOROCYCLOHEXANONE(68223-64-3)

Safety Data

• Hazardous Substances Data: 68223-64-3(Hazardous Substances Data)

Usage

Uses

4-Fluorocyclohexanone is a reactant in the synthetic preparation of rapamycin.

InChI:InChI=1/C6H9FO/c7-5-1-3-6(8)4-2-5/h5H,1-4H2

Upstream product

• 4746-97-8 cyclohexanedione monoethylene ketal 
• 142273-44-7 8-fluoro-1,4-dioxaspiro[4.5]dec-7-ene 
• 556-48-9 1,4-Cyclohexanediol 
• 2976-80-9 4-(benzyloxy)cyclohexan-1-ol 
• 74058-19-8 4-fluorocyclohexan-1-ol 
• 13482-22-9 4-hydroxycyclohexanone 

Downstream Products

• 917771-51-8 N-cyclopropyl-4-fluorocyclohexanamine hydrochloride 
• 917865-88-4 C₉H₁₆FN 

Relevant articles and documents

Photoredox-catalyzed deoxyfluorination of activated alcohols with Selectfluor

Herein we disclose a deoxyfluorination of alcohols with an electrophilic fluorine source via visible-light photoredox catalysis. This radical-mediated C–F coupling is capable of fluorinating secondary and tertiary alcohols efficiently, complementing previously reported nucleophilic deoxyfluorination protocols.

NEW BICYCLIC THIOPHENYLAMIDE COMPOUNDS

The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, A, E and n are as described herein, compositions including the compounds and use thereof as fatty-acid binding protein (FABP) 4/5 inhibitors in the treatment of e.g. type 2 diabetes, atherosclerosis or cancer.

Benzamide derivatives and uses related thereto

Benzamide derivatives of formulae I and II, and pharmaceutically acceptable salts, solvates, stereoisomers, and prodrugs thereof, and pharmaceutical compositions comprising the same, are described and have therapeutic utility, particularly in the treatment of diabetes, obesity, and related conditions and disorders: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, and R12 are defined as provided herein.