6830-84-8

Basic information

• Product Name: Cyclohexanecarboxamide, N-methyl-
• CAS NO: 6830-84-8
• Molecular Formula: C8H15NO
• Molecular Weight: 141.213
• Mol File: 6830-84-8.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: Cyclohexanecarboxamide, N-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanecarboxamide, N-methyl-(6830-84-8)
• EPA Substance Registry System: Cyclohexanecarboxamide, N-methyl-(6830-84-8)

Safety Data

• Hazardous Substances Data: 6830-84-8(Hazardous Substances Data)

Usage

General Description

Cyclohexanecarboxamide, N-methyl- is a chemical compound with the molecular formula C8H15NO. It is an amide, containing a cyclohexane ring and a methyl group attached to the nitrogen atom. Cyclohexanecarboxamide, N-methyl- is used as a solvent, and it has applications in various industries such as pharmaceuticals, agrochemicals, and plastics. It is also used as an intermediate in the production of other chemicals. Cyclohexanecarboxamide, N-methyl- is known to have low toxicity and is considered to be relatively safe for use in industrial processes.

Upstream product

• 88070-48-8 N-methylbenzamide 
• 593-51-1 methylamine hydrochloride 
• 2719-27-9 cyclohexanylcarbonyl chloride 
• 823-76-7 Cyclohexyl methyl ketone 
• 52316-19-5 cyclohexyl methyl ketone oxime 
• 75920-71-7 (1,1-Bis-methylsulfanyl-ethyl)-cyclohexane 
• 80783-98-8 N-methoxy-N-methylcyclohexanecarboxamide 
• 123-39-7 N-Methylformamide 
• 110-83-8 cyclohexene 
• 85462-16-4 N-Methyl-O-p-nitrophenylsulphonylhydroxylamine 
• 2043-61-0 cyclohexanecarbaldehyde 
• 100812-16-6 N-(2,2-dimethylpropanoyl)-N-cyclohexanoylmethanamine 
• 3282-30-2 pivaloyl chloride 
• 89332-91-2 N-(cyclohexylmethylidene)methanamine N-oxide 

Downstream Products

• 52316-19-5 cyclohexyl methyl ketone oxime 
• 98-89-5 Cyclohexanecarboxylic acid 
• 4630-82-4 methyl cyclohexylcarboxylate 
• 68571-10-8 cyclohexyl(pyrrolidin-1-yl)methanone 
• 7469-80-9 cyclohexyl 4-methoxyphenyl ketone 
• 2043-61-0 cyclohexanecarbaldehyde 
• 1192477-32-9 N-(cyclohexylmethyl)-2-(6-methoxy-1H-indol-3-yl)-N-methyl-2-oxoacetamide 
• 1192477-25-0 N-(cyclohexylmethyl)-2-(1H-indol-3-yl)-N-methyl-2-oxoacetamide 
• 6553-81-7 butyl cyclohexanecarboxylate 
• 100-49-2 cyclohexylmethyl alcohol 
• 25756-29-0 N-methylcyclohexylmethylamine 
• 100812-16-6 N-(2,2-dimethylpropanoyl)-N-cyclohexanoylmethanamine 
• 46002-63-5 1-Methyl-5-cyclohexyl-tetrazol 

Relevant articles and documents

Dealkoxylation ofN-alkoxyamides without an external reductant driven by Pd/Al cooperative catalysis

Lewis acid-assisted palladium-catalysed dealkoxylation ofN-alkoxyamides has been developed. This reaction proceeded smoothly with a range ofN-alkoxyamides in the absence of an external reductant, thereby establishing a convenient and reductant-free protocol. In addition, a gram-scale reaction could be achieved. Preliminary mechanistic investigations indicated that β-hydrogen elimination from a palladium alkoxide intermediate generated an intramolecular hydride source.

Efficient one-stage procedure of Beckmann ketones rearrangement in the presence of hydroxylamine

Ketoximes formed from ketones in the presence of hydroxylamine and silica gel in formic acid undergo in situ the Beckmann rearrangement under mild conditions affording in high yields the corresponding amides. Unsymmetrical aromatic ketones, methyl aryl ketones, and methyl cyclohexyl ketone under these conditions form as a rule amides mixtures.

Highly Selective Hydrogenation of Aromatic Ketones and Phenols Enabled by Cyclic (Amino)(alkyl)carbene Rhodium Complexes

Air-stable Rh complexes ligated by strongly σ-donating cyclic (amino)(alkyl)carbenes (CAACs) show unique catalytic activity for the selective hydrogenation of aromatic ketones and phenols by reducing the aryl groups. The use of CAAC ligands is essential for achieving high selectivity and conversion. This method is characterized by its good compatibility with unsaturated ketones, esters, carboxylic acids, amides, and amino acids and is scalable without detriment to its efficiency.