68345-67-5 Usage
Description
6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE-1-ACETIC ACID is a chemical compound with the molecular formula C12H17NO5. It is a derivative of tetrahydroisoquinoline, featuring two methoxy groups at the 6th and 7th positions, and an acetic acid group attached to the 1st position. 6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE-1-ACETIC ACID has potential applications in the pharmaceutical industry due to its unique structure and properties.
Uses
Used in Pharmaceutical Industry:
6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE-1-ACETIC ACID is used as a key intermediate in the synthesis of 5-HT7 receptor antagonists for the treatment of CNS disorders. These antagonists can help regulate serotonin levels in the brain, which may provide therapeutic benefits for various neurological and psychiatric conditions.
In the synthesis of 5-HT7 receptor antagonists, 6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE-1-ACETIC ACID serves as a crucial building block, allowing for the development of new drugs that can target and modulate the activity of the 5-HT7 receptor. This can lead to improved treatment options for patients suffering from CNS disorders, such as depression, anxiety, and schizophrenia.
Check Digit Verification of cas no
The CAS Registry Mumber 68345-67-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,3,4 and 5 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 68345-67:
(7*6)+(6*8)+(5*3)+(4*4)+(3*5)+(2*6)+(1*7)=155
155 % 10 = 5
So 68345-67-5 is a valid CAS Registry Number.
InChI:InChI=1/C13H17NO4/c1-17-11-5-8-3-4-14-10(7-13(15)16)9(8)6-12(11)18-2/h5-6,10,14H,3-4,7H2,1-2H3,(H,15,16)
68345-67-5Relevant articles and documents
Synthesis of the Marine Alkaloids Aaptamine and Demethyloxyaaptamine and of the Parent Structure Didemethoxyaaptamine
Pelletier, Jeffrey C.,Cava, Michael P.
, p. 616 - 622 (2007/10/02)
The first synthesis of the novel marine alkaloids aaptamine and demethyloxyaaptamine is described, as well as the first synthesis of the parent heterocycle 1H-benzonaphthyridine (didemethoxyaaptamine).
