684-76-4 Usage
Description
5,5,5-Trifluoro-4-oxopentanoic acid is an organic compound that serves as a key intermediate in the synthesis of various pharmaceutical compounds. It is characterized by the presence of a trifluoromethyl group and a ketone functional group, which contribute to its unique chemical properties and reactivity.
Uses
Used in Pharmaceutical Industry:
5,5,5-Trifluoro-4-oxopentanoic acid is used as a synthetic intermediate for the production of 2'-trifluoromethyl analogs of indomethacin. These analogs act as selective COX-2 inhibitors, which are important in the development of anti-inflammatory and pain-relieving medications.
Additionally, 5,5,5-trifluoro-4-oxopentanoic acid is involved in the synthesis of indolizine derivatives. Indolizine compounds have potential applications in various therapeutic areas, including the treatment of neurological disorders, cancer, and other diseases. The unique properties of 5,5,5-trifluoro-4-oxopentanoic acid make it a valuable building block in the development of these pharmaceutical agents.
Check Digit Verification of cas no
The CAS Registry Mumber 684-76-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,8 and 4 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 684-76:
(5*6)+(4*8)+(3*4)+(2*7)+(1*6)=94
94 % 10 = 4
So 684-76-4 is a valid CAS Registry Number.
InChI:InChI=1/C5H5F3O3/c6-5(7,8)3(9)1-2-4(10)11/h1-2H2,(H,10,11)
684-76-4Relevant articles and documents
UMWANDLUNG VON α-AMINOSAEUREN IN α-DIKETONE UEBER OXAZOLINZWISCHENSTUFEN
Leyendecker, Joachim,Niewoehner, Ulrich,Steglich, Wolfgang
, p. 2375 - 2378 (2007/10/02)
A four step sequence for the conversion of α-amino acids into α-diketones under mild conditions is desribed.
