6846-12-4

Basic information

• Product Name: 4-Bromo-N-phenylbenzamide
• Synonyms: N-Phenyl 4-bromobenzamide;4-Bromobenzanilide;BenzaMide, 4-broMo-N-phenyl-
• CAS NO: 6846-12-4
• Molecular Formula: C₁₃H₁₀BrNO
• Molecular Weight: 276.13
• Product Categories: blocks;Bromides;Carboxes
• Mol File: 6846-12-4.mol
• Article Data: 64

Chemical Properties

• Melting Point: 205 °C
• Boiling Point: 304.7°C at 760 mmHg
• Flash Point: 138°C
• Appearance: /
• Density: 1.496g/cm³
• Vapor Pressure: 0.000863mmHg at 25°C
• Refractive Index: 1.665
• PKA: 13.14±0.70(Predicted)
• CAS DataBase Reference: 4-Bromo-N-phenylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Bromo-N-phenylbenzamide(6846-12-4)
• EPA Substance Registry System: 4-Bromo-N-phenylbenzamide(6846-12-4)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 6846-12-4(Hazardous Substances Data)

Usage

General Description

4-Bromo-N-phenylbenzamide is a chemical compound with the molecular formula C13H10BrNO. It is a white to light yellow crystalline powder that is primarily used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 4-Bromo-N-phenylbenzamide is known for its role in the development of new drug molecules and has potential applications in the fields of medicinal and agricultural chemistry. It is also utilized as a building block in organic synthesis and as a reagent in various chemical reactions. 4-Bromo-N-phenylbenzamide is an important compound in the field of organic chemistry and holds promise for future research and development.

InChI:InChI=1/C13H10BrNO/c14-11-8-6-10(7-9-11)13(16)15-12-4-2-1-3-5-12/h1-9H,(H,15,16)

Upstream product

• 110-00-9 furan 
• 72730-68-8 C-(4-bromobenzoyl)-N-phenylnitrone 
• 67-56-1 methanol 
• 107590-73-8 N-phenyl-N'-<1-phenyl-1-(4-bromobenzoyl)-2,2,2-trifluoroethyl>carbodiimide 
• 29097-52-7 2,2,4,4-tetramethyl-3-pentanone imine 
• 118364-54-8 N-(1-phenyl-2,2,2-trifluoroethylidene)-N'-4-bromobenzoyl-N'-phenylurea 
• 118364-53-7 1-(4-methylphenyl)-1-(N-phenylcarbodiimido)-2,2,2-trifluoroethyl 4-bromobenzoate 
• 106-54-7 p-Chlorothiophenol 
• 74-11-3 para-chlorobenzoic acid 
• 586-76-5 4-Bromobenzoic acid 
• 62-53-3 aniline 
• 5467-74-3 4-Bromophenylboronic acid 
• 103-71-9 phenyl isocyanate 
• 873-75-6 4-bromobenzenemethanol 

Downstream Products

• 105728-76-5 (4-bromophenyl)[4-(dimethylamino)phenyl]methanone 
• 1253388-63-4 C₂₇H₁₈BrNO 
• 1256360-84-5 C₂₃H₁₈BrNO₃ 
• 1256360-83-4 C₂₄H₂₁NO₄ 
• 62507-50-0 4-bromo-N-(4-nitrophenyl)benzamide 
• 33602-09-4 4-bromo-N-(2-nitrophenyl)benzenamine 
• 301228-28-4 4-bromo-N-(2-(trifluoromethyl)phenyl)benzamide 
• 6127-49-7 2-(4-bromophenyl)indole 
• 949115-03-1 N-phenyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzamide 
• 127580-92-1 (4-bromophenyl)(morpholino)methanone 
• 6911-90-6 N-phenyl 4-bromobenzothioamide 
• 19654-19-4 2-(4-bromophenyl)benzothiazole 
• 540466-42-0 2-(4-bromo-phenyl)-4-phenyl-quinazoline 

Relevant articles and documents

Visible-Light Carbon Nitride-Catalyzed Aerobic Cyclization of Thiobenzanilides under Ambient Air Conditions

A metal-free heterogeneous photocatalysis has been developed for the synthesis of benzothiazoles via intramolecular C-H functionalization/C-S bond formation of thiobenzanilides by inexpensive graphitic carbon nitride (g-C3N4) under visible-light irradiation. This reaction provides access to a broad range of 2-substituted benzothiazoles in high yields under an air atmosphere at room temperature without addition of a strong base or organic oxidizing reagents. In addition, the catalyst was found to be stable and reusable after five reaction cycles.

Regioselective Synthesis of 2° Amides Using Visible-Light-Induced Photoredox-Catalyzed Nonaqueous Oxidative C-N Cleavage of N, N-Dibenzylanilines

A visible-light-driven photoredox-catalyzed nonaqueous oxidative C-N cleavage of N,N-dibenzylanilines to 2° amides is reported. Further, we have applied this protocol on 2-(dibenzylamino)benzamide to afford quinazolinones with (NH4)2S2O8 as an additive. Mechanistic studies imply that the reaction might undergo in situ generation of α-amino radical to imine by C-N bond cleavage followed by the addition of superoxide ion to form amides.

Acetyl nitrate mediated conversion of methyl ketones to diverse carboxylic acid derivatives

The development of a novel acetyl nitrate mediated oxidative conversion of methyl ketones to carboxylic acid derivatives is described. By analogy to the haloform reaction and supported by experimental and computational investigation we propose a mechanism for this transformation.