68483-62-5

Basic information

• Product Name: 1-ethynyl-4,4-dimethylcyclohexanol
• Synonyms: 1-ethynyl-4,4-dimethylcyclohexanol
• CAS NO: 68483-62-5
• Molecular Formula: C₁₀H₁₆O
• Molecular Weight: 152.23344
• Mol File: 68483-62-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-ethynyl-4,4-dimethylcyclohexanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-ethynyl-4,4-dimethylcyclohexanol(68483-62-5)
• EPA Substance Registry System: 1-ethynyl-4,4-dimethylcyclohexanol(68483-62-5)

Safety Data

• Hazardous Substances Data: 68483-62-5(Hazardous Substances Data)

Usage

Functional groups

Alcohol, Ethynyl

Structure

Cyclohexane ring with a triple bond and two methyl groups on the fourth carbon

Reactivity

Can be used as a building block in organic synthesis and as a reagent to introduce ethynyl groups into molecules

Applications

Used in the preparation of various organic compounds

Physical properties

Influenced by the 4,4-dimethylcyclohexanol moiety

Importance

Versatile chemical compound with various applications in organic chemistry

Upstream product

• 4255-62-3 4,4-dimethylcyclohexane-1-one 
• 4301-14-8 acetylenemagnesium bromide 
• 74-86-2 acetylene 

Downstream Products

• 1190962-40-3 1-(2-(2-fluoro-pyridin-3-yl)ethynyl)-4,4-dimethyl-cyclohexan-1-ol 
• 1190962-41-4 1-((Z)-2-(2-fluoro-pyridin-3-yl)-vinyl)-4,4-dimethyl-cyclohexan-1-ol 
• 1554305-12-2 1-((2-(4,4-dimethylcyclohexylidene)vinyl)sulfonyl)-3,5-bis(trifluoromethyl)benzene 
• 68483-61-4 1(4,4-dimethyl-cyclohex-1-en-1-yl)-pent-4-en-1-one 
• 68524-48-1 4,4-Dimethyl-1-pent-4-en-1-ynyl-cyclohexanol 

Relevant articles and documents

Halogen-Substituted Allenyl Ketones through Ring Opening of Nonstrained Cycloalkanols

An efficient synthesis of halogen-substituted allenyl ketones via Ag-catalyzed oxidative ring opening of allenyl cyclic alcohols under mild reaction conditions has been achieved. The reaction features a wide substrate scope and excellent regioselectivity. The synthetic potential of the products has been demonstrated by their conversion to stereodefined alkenes and heterocyclic compounds.

GEM-DISUBSTITUTED AND SPIROCYCLIC AMINO PYRIDINES/PYRIMIDINES AS CELL CYCLE INHIBITORS

Compounds, pharmaceutical compositions and methods are provided that are useful in the treatment of CDK4-mediated disorders, such as cancer. The subject compounds are gem-disubstituted or spirocyclic pyridine, pyrimidine and triazine derivatives.