685111-88-0

Basic information

• Product Name: Pyridine, 4-[(2R,4S)-2-(4-nitrophenoxy)-2-oxido-1,3,2-dioxaphosphorinan-4-yl]-
• CAS NO: 685111-88-0
• Molecular Formula: C14H13N2O6P
• Molecular Weight: 336.241
• Mol File: 685111-88-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Pyridine, 4-[(2R,4S)-2-(4-nitrophenoxy)-2-oxido-1,3,2-dioxaphosphorinan-4-yl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 4-[(2R,4S)-2-(4-nitrophenoxy)-2-oxido-1,3,2-dioxaphosphorinan-4-yl]-(685111-88-0)
• EPA Substance Registry System: Pyridine, 4-[(2R,4S)-2-(4-nitrophenoxy)-2-oxido-1,3,2-dioxaphosphorinan-4-yl]-(685111-88-0)

Safety Data

• Hazardous Substances Data: 685111-88-0(Hazardous Substances Data)

Upstream product

• 777-52-6 1-dichlorophosphoryloxy-4-nitro-benzene 
• 685111-87-9 (-)-(S)-1-(pyridin-4-yl)-1,3-propanediol 
• 1027138-30-2 ethyl 3-(L-2-N,N-dimethylamino-3-phenyl-propanoyloxy)-3-(pyridin-4-yl)-propanoate 
• 1026885-94-8 ethyl 3-(L-2-N,N-dimethylamino-3-phenyl-propanoyloxy)-3-(pyridin-4-yl)-propanoate 
• 872-85-5 pyridine-4-carbaldehyde 
• 100-02-7 4-nitro-phenol 
• 591228-11-4 3-hydroxy-3-(pyridin-4-yl)propionic acid ethyl ester 
• 329325-42-0 (+)-(R)-1-(pyridin-4-yl)-1,3-propanediol 

Downstream Products

• 685111-92-6 (4S)-5'-O-cis-[4-(pyridin-4yl)-2-oxido-1,3,2-dioxaphosphorinan-2yl]-cytosine-β-D-arabinofuranoside 

Relevant articles and documents

Stereoselective synthesis of nucleoside monophosphate HepDirect prodrugs

Synthesis of HepDirect prodrugs of nucleoside monophosphates via phosphorylation with a chiral reagent forms a new asymmetric center at phosphorus and produces two diastereomers. Coupling of chiral phosphoramidite 6 derived from (S)-diol 5 with ara-A foll

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Design, Synthesis, and Characterization of a Series of Cytochrome P 450 3A-Activated Prodrugs (HepDirect Prodrugs) Useful for Targeting Phosph(on)ate-Based Drugs to the Liver

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