6852-47-7

Basic information

• Product Name: N,N-dimethyl-N-(2'-methylphenyl)amine N-oxide
• Synonyms: N,N-dimethyl-N-(2'-methylphenyl)amine N-oxide
• CAS NO: 6852-47-7
• Molecular Weight: 151.208
• Mol File: 6852-47-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N,N-dimethyl-N-(2'-methylphenyl)amine N-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-dimethyl-N-(2'-methylphenyl)amine N-oxide(6852-47-7)
• EPA Substance Registry System: N,N-dimethyl-N-(2'-methylphenyl)amine N-oxide(6852-47-7)

Safety Data

• Hazardous Substances Data: 6852-47-7(Hazardous Substances Data)

Upstream product

• 609-72-3 N,N-dimethyl-o-toluidine 
• 7722-84-1 dihydrogen peroxide 

Downstream Products

• 67761-87-9 4-chloro-N,N,2-trimethylaniline 
• 45848-29-1 2-chloro-6-methyl-N,N-dimethylaniline 
• 50638-49-8 2-methyl-4-bromo-N,N-dimethylaniline 
• 609-72-3 N,N-dimethyl-o-toluidine 
• 1610871-13-0 1,7-dimethyl-2,3-diphenyl-1H-indole 

Relevant articles and documents

Synthesis of Halogenated Anilines by Treatment of N, N-Dialkylaniline N-Oxides with Thionyl Halides

The special reactivity of N,N-dialkylaniline N-oxides allows practical and convenient access to electron-rich aryl halides. A complementary pair of reaction protocols allow for the selective para-bromination or ortho-chlorination of N,N-dialkylanilines in up to 69% isolated yield. The generation of a diverse array of halogenated anilines is made possible by a temporary oxidation level increase of N,N-dialkylanilines to the corresponding N,N-dialkylaniline N-oxides and the excision of the resultant weak N-O bond via treatment with thionyl bromide or thionyl chloride at low temperature.