685513-51-3

Basic information

• Product Name: 1H-Pyrazole-5-carboxylic acid, 4-chloro-3-(1,1-dimethylethyl)-1-methyl-
• Synonyms: 3-tert-butyl-4-chloro-1-methyl-1H-pyrazole-5-carboxylic acid
• CAS NO: 685513-51-3
• Molecular Formula: C9H13ClN2O2
• Molecular Weight: 216.667
• Mol File: 685513-51-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazole-5-carboxylic acid, 4-chloro-3-(1,1-dimethylethyl)-1-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazole-5-carboxylic acid, 4-chloro-3-(1,1-dimethylethyl)-1-methyl-(685513-51-3)
• EPA Substance Registry System: 1H-Pyrazole-5-carboxylic acid, 4-chloro-3-(1,1-dimethylethyl)-1-methyl-(685513-51-3)

Safety Data

• Hazardous Substances Data: 685513-51-3(Hazardous Substances Data)

Usage

General Description

1H-Pyrazole-5-carboxylic acid, 4-chloro-3-(1,1-dimethylethyl)-1-methyl- is a chemical compound with the molecular formula C9H12ClN3O2. It is a derivative of pyrazole and contains a 4-chloro-3-(1,1-dimethylethyl)-1-methyl- group. 1H-Pyrazole-5-carboxylic acid, 4-chloro-3-(1,1-dimethylethyl)-1-methyl- is used in chemical and pharmaceutical research for its potential biological and pharmacological activities. It may have applications in the development of new drugs and therapeutic agents due to its structural features and potential interactions with biological targets. Further research is needed to fully understand the properties and potential uses of this chemical compound.

Upstream product

• 13395-36-3 ethyl trimethylacetopyruvate 
• 1245207-40-2 5-tert-butyl-4-chloro-2-methyl-2H-pyrazole-3-carboxylic acid ethyl ester 
• 133261-10-6 5-tert-butyl-2-methyl-2H-pyrazole-3-carboxylic acid ethyl ester 

Downstream Products

• 1332874-98-2 5-tert-butyl-4-chloro-2-methyl-2H-pyrazole-3-carboxylic acid [3-amino-4-chloro-6-(2-trifluoromethyl-phenyl)-pyridin-2-yl]-amide 
• 1332875-19-0 2-(5-tert-butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-4-methoxy-6-(2-trifluoromethyl-phenyl)-3H-imidazo[4,5-c]pyridine 
• 1332875-29-2 2-(5-tert-butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-6-(2-trifluoromethyl-phenyl)-1H-imidazo[4,5-b]pyrazine 
• 1332875-30-5 5-tert-butyl-4-chloro-2-methyl-2H-pyrazole-3-carboxylic acid [5-bromo-3-(4-methoxy-benzylamino)-pyrazin-2-yl]-amide 
• 1332875-31-6 5-tert-butyl-4-chloro-2-methyl-2H-pyrazole-3-carboxylic acid [3-(4-methoxy-benzylamino)-5-(2-trifluoromethyl-phenyl)-pyrazin-2-yl]-amide 
• 1332875-36-1 2-(5-tert-Butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-5-(2-trifluoromethoxy-phenyl)-1H-imidazo[4,5-b]pyrazine 
• 1332875-43-0 5-tert-butyl-4-chloro-2-methyl-2H-pyrazole-3-carboxylic acid [2-[2-(tert-butyl-dimethyl-silanyloxy)-ethoxy]-3-nitro-6-(2-trifluoromethyl-phenyl)-pyridin-4-yl]-amide 
• 1332875-44-1 2-(5-tert-Butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-4-[2-(tert-butyl-dimethyl-silanyloxy)-ethoxy]-6-(2-trifluoromethyl-phenyl)-3H-imidazo[4,5-d]pyridine 
• 1332874-97-1 5-tert-butyl-4-chloro-2-methyl-2H-pyrazole-3-carboxylic acid [4-chloro-3-nitro-6-(2-trifluoromethyl-phenyl)-pyridin-2-yl]-amide 
• 1332875-06-5 8-(5-tert-butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-6-methyl-2-(2-trifluoromethyl-phenyl)-7H-purine 
• 1332875-04-3 5-tert-butyl-4-chloro-2-methyl-2H-pyrazole-3-carboxylic acid [6-methyl-5-nitro-2-(2-trifluoromethyl-phenyl)-pyrimidin-4-yl]-amide 
• 1332875-18-9 5-tert-butyl-4-chloro-2-methyl-2H-pyrazole-3-carboxylic acid [2-methoxy-3-nitro-6-(2-trifluoromethyl-phenyl)-pyridin-4-yl]-amide 
• 1332875-39-4 2-[2-(5-tert-butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-6-(2-trifluoromethyl-phenyl)-3H-imidazo[4,5-c]pyridin-4-yloxy]-ethanol 
• 1332875-48-5 [2-(5-tert-butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-6-(2-trifluoromethyl-phenyl)-3H-imidazo[4,5-c]pyridin-4-yloxy]-acetic acid 

Relevant articles and documents

SUBSTITUTED BENZIMDAZOLE DERIVATIVES USEFUL AS TRPM8 RECEPTOR MODULATORS

The present invention is directed to benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by TRP M8, including for example, inflammatory pain, inflammatory hyperalgesia