68612-69-1Relevant articles and documents
NBE-Controlled Palladium-Catalyzed Interannular Selective C-H Silylation: Access to Divergent Silicon-Containing 1,1′-Biaryl-2-Acetamides
Li, Wenguang,Chen, Wenqi,Zhou, Bang,Xu, Yankun,Deng, Guobo,Liang, Yun,Yang, Yuan
, p. 2718 - 2722 (2019/04/16)
A novel palladium-catalyzed interannular selective C-H silylation of 1,1′-biaryl-2-acetamides is described. The combination of palladium catalyst with copper oxidant enables meta- or ortho-selective C-H silylation by employing hexamethyldisilane as a trimethylsilyl source, which relies on the control of NBE derivatives as a switch, thus providing straightforward access to divergent silicon-containing 1,1′-biaryl-2-acetamides.
Highly effective Pd-catalyzed ortho olefination of acetanilides: Broad substrate scope and high tolerability
Kim, Byung Seok,Jang, Chungsik,Lee, Dong Jin,Youn, So Won
, p. 2336 - 2340 (2011/06/25)
Bring it on! An effective Pd-catalyzed ortho olefination of various acetanilides has been developed. This transformation has a broad substrate scope and wide functional-group tolerability, regardless of the electronic and steric properties of acetanilide substrates, providing a straightforward access to highly functionalized arenes.
