68748-07-2

Basic information

• Product Name: N-(2-BROMO-4-ISOPROPYL-PHENYL)-ACETAMIDE
• Synonyms: N-(2-BROMO-4-ISOPROPYL-PHENYL)-ACETAMIDE;4-Acetamido-3-bromocumene
• CAS NO: 68748-07-2
• Molecular Formula: C₁₁H₁₄BrNO
• Molecular Weight: 256.13896
• Mol File: 68748-07-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 366.4°Cat760mmHg
• Flash Point: 175.4°C
• Appearance: /
• Density: 1.356g/cm³
• Vapor Pressure: 1.47E-05mmHg at 25°C
• Refractive Index: 1.575
• Storage Temp.: Room temperature.
• CAS DataBase Reference: N-(2-BROMO-4-ISOPROPYL-PHENYL)-ACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-BROMO-4-ISOPROPYL-PHENYL)-ACETAMIDE(68748-07-2)
• EPA Substance Registry System: N-(2-BROMO-4-ISOPROPYL-PHENYL)-ACETAMIDE(68748-07-2)

Safety Data

• Hazardous Substances Data: 68748-07-2(Hazardous Substances Data)

Usage

General Description

N-(2-Bromo-4-isopropyl-phenyl)-acetamide is a chemical compound with the molecular formula C11H14BrNO. It is an organic compound consisting of a benzene ring substituted with a bromine atom and an isopropyl group, as well as an acetamide functional group. It is commonly used in organic synthesis and pharmaceutical research as a building block for the preparation of other organic compounds and pharmaceuticals. N-(2-BROMO-4-ISOPROPYL-PHENYL)-ACETAMIDE may also have potential applications in the field of medicinal chemistry, where it could be used in the development of new drugs and therapeutic agents. Additionally, it may have uses in the manufacturing of specialty chemicals and materials.

InChI:InChI=1/C11H14BrNO/c1-7(2)9-4-5-11(10(12)6-9)13-8(3)14/h4-7H,1-3H3,(H,13,14)

Upstream product

• 99-88-7 4-Isopropylaniline 
• 51605-97-1 2-bromo-4-isopropylaniline 
• 108-24-7 acetic anhydride 
• 5702-74-9 N-(4-iso-propylphenyl)acetamide 

Downstream Products

• 895239-75-5 (E)-3-(3-isopropylphenyl)acrylaldehyde 
• 457928-84-6 (S)-3-(3-isopropylphenyl)butanal 
• 79069-38-8 2-(acetylamino)-5-(1-methylethyl)benzoic acid 
• 68701-44-0 2-cyano-4-isopropylacetanilide 
• 880081-44-7 2-isopropenyl-4-isopropylaniline 
• 880081-42-5 N-(2-isopropenyl-4-isopropyl-phenyl)-acetamide 
• 530403-36-2 N-[4-isopropyl-2-(dibenzoselenophene-4-yl)phenyl]acetamide 

Relevant articles and documents

Site-Specific Synthesis of Carbazole Derivatives through Aryl Homocoupling and Amination

We synthesized various carbazoles from anilines through a three-step process with good overall yields (up to 48percent). This process comprises N -acetylation, copper(0)-mediated Ullmann homocoupling, and acid-mediated intramolecular amination. It permits various functional groups on the substrate. Scale-up of the developed three-step synthetic route to carbazoles was also demonstrated.

A Visible Light-Mediated Regioselective Halogenation of Anilides and Quinolines by Using a Heterogeneous Cu-MnO Catalyst

A simple and practical heterogeneous Cu-MnO catalyzed regioselective halogenation of anilides and quinolines under irradiation with household 40 W incandescent lamp was developed. This method uses a recyclable Cu-MnO catalyst, acetonitrile as an industrially friendly solvent, and economic N-halo succinimides as a halogenating source. The reaction is scalable and well tolerated with a broad range of functional groups.

Sulfonamides having antiangiogenic and anticancer activity

Compounds having methionine aminopeptidase-2 inhibitory (MetAP2) are described. Also described are pharmaceutical compositions comprising the compounds, methods of treatment using the compounds, methods of inhibiting angiogenesis, and methods of treating cancer.