68750-24-3

Basic information

• Product Name: 1,6-Hexanediol, monoacetate
• CAS NO: 68750-24-3
• Molecular Formula: C8H16O3
• Molecular Weight: 160.213
• Mol File: 68750-24-3.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 1,6-Hexanediol, monoacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,6-Hexanediol, monoacetate(68750-24-3)
• EPA Substance Registry System: 1,6-Hexanediol, monoacetate(68750-24-3)

Safety Data

• Hazardous Substances Data: 68750-24-3(Hazardous Substances Data)

Usage

Physical State

Colorless, odorless liquid

Uses

Solvent in chemical production
Intermediate in the production of perfumes, polyester resins, and adhesives
Plasticizer, viscosity modifier, and humectant in cosmetics and personal care products

Antimicrobial Properties

Used as a preservative in various products

Safety

Relatively safe for use in consumer products when used as directed and in accordance with regulatory guidelines.

Upstream product

• 1178555-31-1 O-6-(benzyloxy)hexyl-S-methyl xanthate 
• 629-11-8 1,6-hexanediol 
• 75-05-8 acetonitrile 
• 653564-21-7 6-(tert-butyldimethylsilyloxy)hexyl acetate 
• 846539-29-5 6-({4-[(trimethylsilyl)methyl]benzyl}oxy)hexyl acetate 
• 108-05-4 vinyl acetate 
• 2466-76-4 N-Acetylimidazole 
• 141-78-6 ethyl acetate 
• 108-24-7 acetic anhydride 
• 6222-17-9 1,6-diacetoxyhexane 

Downstream Products

• 121671-77-0 6-{[tert-butyl(diphenyl)silyl]oxy}hexan-1-ol 
• 118794-70-0 6-(t-butyldiphenylsilyloxy)hexanal 
• 118794-76-6 2-<5-(tert-Butyldiphenylsiloxy)pentan-1-yl>-1,3-dithiane 
• 629-11-8 1,6-hexanediol 
• 881304-14-9 {[2-(6-acetoxy-1-dibenzylamino-hexyl)-4-benzyl-oxazol-5-yl]-methyl-amino}-acetic acid methyl ester 
• 881304-19-4 ({2-[5-acetoxy-1-(2-methylcarbamoyl-pyrrolidin-1-yl)-pentyl]-4-benzyl-oxazol-5-yl}-methyl-amino)-acetic acid methyl ester 
• 881304-16-1 {[2-(6-acetoxy-1-morpholin-4-yl-hexyl)-4-benzyl-oxazol-5-yl]-methyl-amino}-acetic acid methyl ester 
• 881304-15-0 {[2-(6-acetoxy-1-dibenzylamino-hexyl)-oxazol-5-yl]-methyl-amino}-acetic acid methyl ester 
• 846539-29-5 6-({4-[(trimethylsilyl)methyl]benzyl}oxy)hexyl acetate 
• 77295-58-0 1-acetoxy-6-iodohexane 

Relevant articles and documents

Expanding the scope of methyl xanthate esters - From Barton-McCombie reaction auxiliary to versatile protective group

The methyl xanthate ester is presented as a versatile protective group for alcohols. Hydroxyl groups can easily be transformed into methyl xanthate esters by several methods and are commonly used as an auxiliary in the Barton-McCombie reaction. We show that these methyl xanthate esters can readily and chemoselectively be cleaved under mild conditions by the action of diethylenetriamine using microwave heating. This method is orthogonal to many common hydroxyl protective groups that can be introduced and cleaved in the presence of methyl xanthate ester.

N,N-diarylammonium pyrosulfate as a highly effective reverse micelle-type catalyst for hydrolysis of esters

Reverse micelle-type N,N-diarylammonium pyrosulfate (3-5 mol %) efficiently catalyzes the hydrolysis of esters (up to 100 mmol scale) under organic solvent-free conditions. The present method is successfully applied to the hydrolysis of various esters without the decomposition of the base-sensitive moieties and without any loss of optical purity for α-heterosubstituted carboxylic acids.

Lipase-catalysed selective monoacylation of 1,n-diols with vinyl acetate

A simple enzymatic methodology for the selective monoacetylation of 1,n-diols (n=5,8) using vinyl acetate is reported. Monoacetylation excesses of 81-87% at 74-90% 1,n-diol conversions were obtained in toluene and diisopropyl ether using Thermomyces lanuginosus lipase (TLL) immobilised on polypropylene powder as catalyst.