68905-99-7

Basic information

• Product Name: 4(1H)-Pyrimidinone, 6-hydroxy-5-nitro-2-phenyl-
• Synonyms: 5-NITRO-2-PHENYL-4,6-PYRIMIDINEDIOL
• CAS NO: 68905-99-7
• Molecular Formula: C₁₀H₇N₃O₄
• Molecular Weight: 233.18
• Mol File: 68905-99-7.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4(1H)-Pyrimidinone, 6-hydroxy-5-nitro-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4(1H)-Pyrimidinone, 6-hydroxy-5-nitro-2-phenyl-(68905-99-7)
• EPA Substance Registry System: 4(1H)-Pyrimidinone, 6-hydroxy-5-nitro-2-phenyl-(68905-99-7)

Safety Data

• Hazardous Substances Data: 68905-99-7(Hazardous Substances Data)

Upstream product

• 13566-71-7 2-Phenyl-4,6-dihydroxy-pyrimidine 
• 17424-17-8 6-phenyl-pyridine-2,4-diol 
• 1670-14-0 benzamidine monohydrochloride 

Downstream Products

• 1415583-54-8 C₂₂H₃₃N₇O₂ 
• 1415583-53-7 C₂₂H₃₁N₇O₄ 
• 1415583-40-2 C₂₃H₃₁N₇O₃ 
• 1415583-43-5 C₂₃H₃₁N₇O₂ 
• 192631-79-1 N-Benzyl-N'-cyclohexyl-5-nitro-2-phenyl-pyrimidine-4,6-diamine 
• 192631-83-7 N,N'-Dicyclohexyl-5-nitro-2-phenyl-pyrimidine-4,6-diamine 
• 192631-81-5 N-Benzyl-5-nitro-N'-pentyl-2-phenyl-pyrimidine-4,6-diamine 
• 192631-78-0 N-Benzyl-N'-cyclopentyl-5-nitro-2-phenyl-pyrimidine-4,6-diamine 
• 192631-77-9 N,N'-Dibenzyl-5-nitro-2-phenyl-pyrimidine-4,6-diamine 
• 192631-80-4 N-Benzyl-N'-butyl-5-nitro-2-phenyl-pyrimidine-4,6-diamine 
• 192631-85-9 5-Nitro-N,N'-dipentyl-2-phenyl-pyrimidine-4,6-diamine 
• 68921-91-5 2-Phenyl-5-nitro-4,6-dichloro-pyrimidine 

Relevant articles and documents

NOVEL IMMUNE SYSTEM MODULATORS

The present invention relates to a compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein the symbols are as defined in the specification; a pharmaceutical composition comprising the same; and a method for treating or preventing autoimmunity disease using the same.

Synthesis of 4,6-disubstituted- and 4,5,6-trisubstituted-2-phenyl- pyrimidines and their affinity towards A1 adenosine receptors

Synthesis and assay of title compounds are reported. The results can support our hypothesis about the possibility that molecules characterized by great flexibility, as the title 2-phenyl-4,5,6-triaminopyrimidines, can better interact with the receptor sites compared with rigid molecules as 2,6,9-trisubstituted 8-azaadenines. Relatively low activity shown by pyrimidine derivatives demonstrated the importance of the bicyclic aromatic system in 8-azaadenines and adenines to give a favourable interaction between a hexogenous molecule and the A1 adenosine receptors.

CERTAIN CYCLOALKYL AND AZACYCLOALKYL PYRROLOPYRIMIDINES; A NEW CLASS OF GABA BRAIN RECEPTOR LIGANDS

The invention encompasses a compound of the formula STR1 and the pharmaceutically acceptable non-toxic salts thereof wherein X, W, Y, R, and R2 are variables.These compounds are highly selective agonists, antagonists or inverse agonists for GABAa brain receptors or prodrugs thereof and are useful in the diagnosis and treatment of anxiety, sleep, and seizure disorders, overdose with benzodiazepine type drugs, and enhancement of alertness.