68972-93-0

Basic information

• Product Name: Benzene, 1,1'-[(2E)-2-butene-1,4-diylbis(oxymethylene)]bis-
• Synonyms: (E)-1,4-bis(benzyloxy)-2-butene;1,4-bis-benzyloxy-but-2t-ene;(E)-1,4-dibenzyloxybut-2-ene;1,4-Dibenzyloxy-2-butene;(E)-1,4-bis(benzyloxy)but-2-ene;trans-1,4-dibenzyloxy-2-butene
• CAS NO: 68972-93-0
• Molecular Formula: C18H20O2
• Molecular Weight: 268.356
• Mol File: 68972-93-0.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: Benzene, 1,1'-[(2E)-2-butene-1,4-diylbis(oxymethylene)]bis-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,1'-[(2E)-2-butene-1,4-diylbis(oxymethylene)]bis-(68972-93-0)
• EPA Substance Registry System: Benzene, 1,1'-[(2E)-2-butene-1,4-diylbis(oxymethylene)]bis-(68972-93-0)

Safety Data

• Hazardous Substances Data: 68972-93-0(Hazardous Substances Data)

Upstream product

• 821-06-7 (E)-1,4-dibromobutene 
• 100-51-6 benzyl alcohol 
• 14593-43-2 benzyl allyl ether 
• 821-11-4 trans-butene-1,4-diol 
• 100-39-0 benzyl bromide 
• 100-44-7 benzyl chloride 
• 136458-56-5 2,3-bis((benzyloxy)methyl)oxirane 
• 68972-96-3 (Z)-1,4-dibenzyloxy-2-butene 
• 162369-37-1 2,3-bis((benzyloxy)methyl)thiirane 

Downstream Products

• 68972-94-1 (2R*,3R*)-2,3-bis((benzyloxy)methyl)oxirane 
• 91604-41-0 (R,R)-1,4-dibenzylthreitol 
• 69010-01-1 (2R*,3S*)-1,4-bis(benzyloxy)butane-2,3-diol 
• 1271145-22-2 (2R*,3S*)-2,3-bis(benzyloxymethyl)-1,4-dioxane 
• 167841-04-5 2-benzyloxymethyl-6-methyl-2,3-dihydro-4H-pyran-4-one 
• 1309474-32-5 (+)-(S)-(((2-vinyloctyl)oxy)methyl)benzene 
• 68973-05-7 (2R*,3S*)-2,3-bis((benzyloxy)methyl)oxirane 
• 60656-87-3 benzyloxyacetoaldehyde 
• 132398-78-8 9-((2R,3R)-2,3-Bis-benzyloxymethyl-cyclopropyl)-6-chloro-9H-purine 
• 132398-79-9 9-((2R,3R)-2,3-Bis-benzyloxymethyl-cyclopropyl)-9H-purin-6-ylamine 
• 132398-81-3 1-((2R,3R)-2,3-Bis-benzyloxymethyl-cyclopropyl)-3-((E)-3-methoxy-2-methyl-acryloyl)-urea 
• 132398-77-7 N⁴-((2R,3R)-2,3-Bis-benzyloxymethyl-cyclopropyl)-6-chloro-pyrimidine-4,5-diamine 

Relevant articles and documents

Synthesis of 5-thiodidehydropyranylcytosine derivatives as potential anti-HIV agents

As a part of our ongoing efforts to identify new anti-HIV agents, a 5′-thiopyrano-nucleoside derivative 4, designed based on 4′-thioD4C 1 and cyclohexenylnucleoside 3, was synthesized. The dihydrothiopyran skeleton of 4 was constructed by the ring closing metathesis of 21 which was synthesized from but-2-yne-1,4-diol. After converting the protecting group from MOM to TBS followed by oxidation, a Pummerer-type thioglycosylation reaction of 24 with persilylated uracil gave the desired 5-thiodihydrothiopyranyluracils 25 and 26 as a mixture of anomers. The conversion of 25 to a cytosine derivative and subsequent deprotection gave a 5-thiodidehydropyranosylcytosine derivative 4 in good yield. The anti-HIV activity of 4 was also evaluated.

Highly Z-selective olefins metathesis

The present invention relates generally to catalysts and processes for the Z-selective formation of internal olefin(s) from terminal olefin(s) via homo-metathesis reactions.

E/Z product distribution in the metathesis of allyl alcohol derivatives with a first generation ruthenium-based catalyst

Based on experiments with four simple derivatives of allyl alcohol, it has been shown that the product of cross-metathesis as mediated by a 'first generation' ruthenium catalyst increases in its proportion of the E-isomer as the reaction progresses. This increase is due to equilibration, which is also mediated by the ruthenium catalyst.