69015-51-6 Usage
Structure
Bicyclic heterocyclic compound with a chlorine atom and an ethyl group attached to the benzimidazole ring
Usage
Intermediate in the synthesis of various pharmaceuticals and organic compounds, suitable for the development of new drugs and related pharmaceutical research
Industrial and scientific applications
Suitable due to its structural properties
Check Digit Verification of cas no
The CAS Registry Mumber 69015-51-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,0,1 and 5 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 69015-51:
(7*6)+(6*9)+(5*0)+(4*1)+(3*5)+(2*5)+(1*1)=126
126 % 10 = 6
So 69015-51-6 is a valid CAS Registry Number.
69015-51-6Relevant articles and documents
Indole RSK inhibitors. Part 2: Optimization of cell potency and kinase selectivity
Kirrane, Thomas M.,Boyer, Stephen J.,Burke, Jennifer,Guo, Xin,Snow, Roger J.,Soleymanzadeh, Lida,Swinamer, Alan,Zhang, Yunlong,Madwed, Jeffery B.,Kashem, Mohammed,Kugler, Stanley,O'Neill, Margaret M.
, p. 738 - 742 (2012/03/11)
A series of inhibitors for the 90 kDa ribosomal S6 kinase (RSK) based on an 1-oxo-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,2-a]indole-8-carboxamide scaffold were optimized for cellular potency and kinase selectivity. This led to the identification of compound 24, BIX 02565, an attractive candidate for use in vitro and in vivo to explore the role of RSK as a target for the treatment heart failure.
