69039-10-7Relevant articles and documents
Acylation of Phosphorus-Substituted CH Acids under the Conditions of Phase-transfer Catalysis III. Acylation of Thiophosphinoylacetonitriles
Odinets,Artyushin,Kalyanova,Petrovskii,Lysenko,Antipin,Struchkov,Mastryukova,Kabachnik
, p. 43 - 53 (2007/10/03)
Acylation of thiophosphinoylacetonitriles under the conditions of phase-transfer catalysis involves the central carbon atom with formation of C-acyl derivatives in the enol form (Z-isomers) stabilized by intramolecular hydrogen bonding. Acylation with aromatic acyl halides also gives products of double C,O-acylation (Z-isomers), often predominating in amount. The yield of acylation products is affected by substituents at the phosphorus atom, the nature of acylating agent, and reaction conditions. The data of X-ray structural investigations of single crystals of (diphenylthiophosphinoyl)acetylacetonitrile enol and [isobutoxy(methyl)thiophosphinoylbenzoylacetonitrile enol benzoate are presented.
