69141-46-4Relevant articles and documents
Identification of 4-isopropyl-thiotropolone as a novel anti-microbial: Regioselective synthesis, NMR characterization, and biological evaluation
Elagawany, Mohamed,Hegazy, Lamees,Cao, Feng,Donlin, Maureen J.,Rath, Nigam,Tavis, John,Elgendy, Bahaa
, p. 29967 - 29975 (2018)
We have synthesized and separated tosylated thujaplicin isomers for the first time, and elucidated their structures using 1D, 2D-NMR techniques and X-ray crystallography. The tosylated isomers were used to synthesize 4-isopropyl-thiotropolone and 6-isopro
New copper(II) 2-(alkylamino)troponates
Barret, Marie C.,Bhatia, Purvi H.,Kociok-Koehn, Gabriele,Molloy, Kieran C.
, p. 543 - 551 (2014/08/05)
The copper aminotropones Cu[ON(R′)C7H4R-4] 2 [R = H, R′ = Me (13), Et (14), n-Pr (15), n-Bu (16), Bz (17), MenOCH2CH2 (20); R = i-Pr, R′ = Me (18), n-Pr (19), MenOCH2CH2 (21)] have been prepared from the corresponding aminotropones HN(R′)OC7H4R-4 (1-7) by reacting with copper(II) acetate in aqueous ethanol. 20, 21 contain the flavourant, menthol, as part of the ligand. The structures of 5 (R = H, R′ = Bz), a hydrogen-bonded dimer, 14 and 20, both incorporating square-planar, four-coordinate copper centres, have been determined by X-ray crystallography. The antibacterial activities of complexes 13, 17, 20 and 21 have been assayed against Staphylococcus waneri, an in vitro model of plaque inhibition effects, and found to be more active than a commercial toothpaste formulation, but less active than the O,O-chelated copper(II) complex of ethylmaltol.
Studies on anti-ulcer agents. II. Synthesis and anti-ulcer activities of 6-isopropylazulene-1-sodium sulfonate derivatives
Yanagisawa,Kosakai,Tomiyama,Yasunami,Takase
, p. 3355 - 3358 (2007/10/02)
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