69146-59-4

Basic information

• Product Name: 1,3,5-Tris((N,N,N-2,3-dihydroxybenzoyl)aminomethyl)benzene
• CAS NO: 69146-59-4
• Molecular Formula: C₃₀H₂₇N₃O₉
• Molecular Weight: 573.559
• Mol File: 69146-59-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 903°Cat760mmHg
• Flash Point: 499.9°C
• Density: 1.496g/cm³
• CAS DataBase Reference: 1,3,5-Tris((N,N,N-2,3-dihydroxybenzoyl)aminomethyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,5-Tris((N,N,N-2,3-dihydroxybenzoyl)aminomethyl)benzene(69146-59-4)
• EPA Substance Registry System: 1,3,5-Tris((N,N,N-2,3-dihydroxybenzoyl)aminomethyl)benzene(69146-59-4)

Safety Data

• Hazardous Substances Data: 69146-59-4(Hazardous Substances Data)

Usage

Chemical structure

A benzene ring with three attached molecules of N,N,N-2,3-dihydroxybenzoylamine.

Composition

Made up of carbon, hydrogen, oxygen, and nitrogen atoms.

Functional groups

Contains amide, hydroxyl, and aromatic groups.

Molecular weight

Approximately 463.43 g/mol

Appearance

Likely a solid or crystalline material, though the exact appearance is not provided in the material.

Applications

Used in the development of functional materials and has potential applications in supramolecular chemistry, organic electronics, and photovoltaics.

Structural properties

Unique structural properties make it suitable for use in various fields.

Electronic properties

Unique electronic properties make it a promising candidate for further research and development in materials science.

Research potential

Its molecular structure and properties make it a promising candidate for further research and development in the field of materials science.

Upstream product

• 90734-96-6 C₇₂H₆₃N₃O₉ 
• 77372-56-6 1,3,5-tris(aminomethyl)benzene 
• 69146-58-3 2,3-bis(benzyloxy)benzoyl chloride 
• 303-38-8 2,3-Dihydroxybenzoic acid 
• 486-79-3 2,3-diacetoxybenzoic acid 
• 18226-42-1 1,3,5-Tris(bromomethyl)benzene 

Downstream Products

• 69058-77-1 Fe⁽³⁺⁾*(C₆H₃(O)2CONHCH₂)3C₆H₃^(6-)=Fe(C₆H₃O₂CONHCH₂)3C₆H₃^(3-) 
• 85710-20-9 ⁽⁵⁷⁾Fe⁽³⁺⁾*C₆H₃(C₆H₃O₂CONHCH₂)3^(6-)=⁽⁵⁷⁾Fe(C₆H₃O₂CONHCH₂)3C₆H₃^(3-) 

Relevant articles and documents

Antibiotic Conjugates with an Artificial MECAM-Based Siderophore Are Potent Agents against Gram-Positive and Gram-Negative Bacterial Pathogens

The development of novel drugs against Gram-negative bacteria represents an urgent medical need. To overcome their outer cell membrane, we synthesized conjugates of antibiotics and artificial siderophores based on the MECAM core, which are imported by bacterial iron uptake systems. Structures, spin states, and iron binding properties were predicted in silico using density functional theory. The capability of MECAM to function as an effective artificial siderophore in Escherichia coli was proven in microbiological growth recovery and bioanalytical assays. Following a linker optimization focused on transport efficiency, five β-lactam and one daptomycin conjugates were prepared. The most potent conjugate 27 showed growth inhibition of Gram-positive and Gram-negative multidrug-resistant pathogens at nanomolar concentrations. The uptake pathway of MECAMs was deciphered by knockout mutants and highlighted the relevance of FepA, CirA, and Fiu. Resistance against 27 was mediated by a mutation in the gene encoding ExbB, which is involved in siderophore transport.