69169-37-5

Basic information

• Product Name: Benz-(1,4-dimethylpent-4-enyl)-amid
• CAS NO: 69169-37-5
• Molecular Weight: 217.311
• Mol File: 69169-37-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benz-(1,4-dimethylpent-4-enyl)-amid(CAS DataBase Reference)
• NIST Chemistry Reference: Benz-(1,4-dimethylpent-4-enyl)-amid(69169-37-5)
• EPA Substance Registry System: Benz-(1,4-dimethylpent-4-enyl)-amid(69169-37-5)

Safety Data

• Hazardous Substances Data: 69169-37-5(Hazardous Substances Data)

Upstream product

• 3240-09-3 5-methyl-5-hexen-2-one 

Relevant articles and documents

Remote Radical Desaturation of Unactivated C?H Bonds in Amides

Desaturation of inert aliphatic C?H bonds in alkanes to form the corresponding alkenes is challenging. In this communication, a new and practical strategy for remote site-selective desaturation of amides via radical chemistry is reported. The readily installed N-allylsulfonylamide moiety serves as an N radical precursor. Intramolecular 1,5-hydrogen atom transfer from an inert C?H bond to the N-radical generates a translocated C-radical which is subsequently oxidized and deprotonated to give the corresponding alkene. The commercially available methanesulfonyl chloride is used as reagent and a Cu/Ag-couple as oxidant. The remote desaturation is realized on different types of unactivated sp3-C?H bonds. The potential synthetic utility of this method is further demonstrated by the dehydrogenation of natural product derivatives and drugs.