691862-94-9

Basic information

• Product Name: 3-[1-(2-fluoro-phenyl)-1H-pyrrol-3-yl]-5-hydroxymethyl-oxazolidin-2-one
• CAS NO: 691862-94-9
• Molecular Weight: 276.267
• Mol File: 691862-94-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-[1-(2-fluoro-phenyl)-1H-pyrrol-3-yl]-5-hydroxymethyl-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[1-(2-fluoro-phenyl)-1H-pyrrol-3-yl]-5-hydroxymethyl-oxazolidin-2-one(691862-94-9)
• EPA Substance Registry System: 3-[1-(2-fluoro-phenyl)-1H-pyrrol-3-yl]-5-hydroxymethyl-oxazolidin-2-one(691862-94-9)

Safety Data

• Hazardous Substances Data: 691862-94-9(Hazardous Substances Data)

Upstream product

• 60456-26-0 (R)-glycidyl butyrate 
• 691862-82-5 [1-(2-fluoro-phenyl)-1H-pyrrol-3-yl]-carbamic acid benzyl ester 
• 691862-72-3 1-(2-fluoro-phenyl)-1H-pyrrole-3-carboxylic acid 
• 348-54-9 2-Fluoroaniline 

Downstream Products

• 691863-06-6 methanesulfonic acid 3-[1-(2-fluoro-phenyl)-1H-pyrrol-3-yl]-2-oxo-oxazolidin-5-ylmethyl ester 
• 691863-30-6 5-aminomethyl-3-[1-(2-fluoro-phenyl)-1H-pyrrol-3-yl]-oxazolidin-2-one 
• 691863-18-0 5-azidomethyl-3-[1-(2-fluoro-phenyl)-1H-pyrrol-3-yl]-oxazolidin-2-one 

Relevant articles and documents

Synthesis and in vitro antimycobacterial activity of novel 3-(1H-pyrrol-1-yl)-2-oxazolidinone analogues of PNU-100480

Pursuing our search program for new antitubercular drugs we decided to explore the potentiality of oxazolidinone moiety by synthesizing novel 3-(1H-pyrrol-1-yl)-2-oxazolidinone analogues of PNU-100480. The new derivatives were tested against atypical mycobacteria as well as against drug resistant Mycobacterium tuberculosis and some of them exhibited a fairly good activity against Mycobacterium avium complex (MAC).