69187-60-6 Usage
Description
(2,2-Dimethyl-1-phenylpropyl)ammonium-chloride, also known as Seebag's reagent, is a quaternary ammonium salt that is commonly used as a phase-transfer catalyst. It is an organic compound with the chemical formula C13H20ClN and a molecular weight of 227.75 g/mol. (2,2-Dimethyl-1-phenylpropyl)ammonium-chlorid is a white to off-white crystalline solid that is soluble in organic solvents but not in water.
Uses
Used in Organic Synthesis:
(2,2-Dimethyl-1-phenylpropyl)ammonium-chloride is used as a phase-transfer catalyst for facilitating the transfer of reactants between immiscible phases in organic synthesis reactions. This allows for more efficient and selective reactions.
Used in Pharmaceutical Industry:
(2,2-Dimethyl-1-phenylpropyl)ammonium-chloride is used in the preparation of biologically active compounds and pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 69187-60-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,1,8 and 7 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 69187-60:
(7*6)+(6*9)+(5*1)+(4*8)+(3*7)+(2*6)+(1*0)=166
166 % 10 = 6
So 69187-60-6 is a valid CAS Registry Number.
69187-60-6Relevant articles and documents
Synthesis of α-Substituted Primary Benzylamines through Copper-Catalyzed Cross-Dehydrogenative Coupling
Kramer, S?ren
supporting information, p. 65 - 69 (2019/01/04)
A copper-catalyzed route to α-substituted, primary benzylamines by C-H functionalization of alkylarenes is described. The method directly affords the amine hydrochloride salt. Catalyst loadings down to 0.1 mol % in combination with scalability, insensitivity to air and moisture, and no need for column chromatography makes the procedure highly practical. The facile synthesis of the racemate of a blockbuster drug highlights the relevance for the development of pharmaceuticals. Preliminary mechanistic data are also included.
