691885-26-4

Basic information

• Product Name: dl-4-bromo-N-(tert-butoxycarbonyl)tryptophan
• CAS NO: 691885-26-4
• Molecular Weight: 383.242
• Mol File: 691885-26-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: dl-4-bromo-N-(tert-butoxycarbonyl)tryptophan(CAS DataBase Reference)
• NIST Chemistry Reference: dl-4-bromo-N-(tert-butoxycarbonyl)tryptophan(691885-26-4)
• EPA Substance Registry System: dl-4-bromo-N-(tert-butoxycarbonyl)tryptophan(691885-26-4)

Safety Data

• Hazardous Substances Data: 691885-26-4(Hazardous Substances Data)

Upstream product

• 691885-32-2 (S)-4-bromo-N-(tert-butoxycarbonyl)tryptophan methyl ester 

Downstream Products

• 219943-61-0 (R)-4-bromotryptophan 
• 52448-16-5 (S)-2-amino-3-(4-bromo-1H-indol-3-yl)propanoic acid 

Relevant articles and documents

General synthesis of unnatural 4-, 5-, 6-, and 7-bromo-D-tryptophans by means of a regioselective indole alkylation

A general two-step approach to enantiopure bromotryptophans from unprotected bromoindoles has been developed. Indole nucleophiles prepared with MeMgCl in the presence of CuCl reacted with cyclic sulfamidates derived from enantiopure D-serine to form 4-, 5-, 6-, or 7-bromo-D-tryptophan and some other halogenated tryptophans in moderate yields but with complete regioselectivity. The bromotryptophan derivatives were deprotected using mild conditions.